Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.66 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19945842 | 0.92 | TLR7 (0.66) | TLR7TLR8 | |
| SCHEMBL18237058 | 0.91 | TLR7 (0.66) | TLR7TLR8 | |
| SCHEMBL21318954 | 0.91 | TLR7 (0.65) | TLR7TLR8 | |
| SCHEMBL20106984 | 0.88 | TLR7 (0.58) | TLR7TLR8 | |
| Propane SCHEMBL28675793 | 0.85 | TLR7 (0.62) | TLR7TLR8 | |
| SCHEMBL21318933 | 0.83 | TLR7 (0.66) | TLR7TLR8 | |
| SCHEMBL21318931 | 0.83 | TLR7 (0.65) | TLR7TLR8 | |
| SCHEMBL21319061 | 0.82 | TLR7 (0.66) | TLR7TLR8 | |
| SCHEMBL21318949 | 0.81 | TLR7 (0.63) | TLR7 | |
| SCHEMBL21318965 | 0.81 | TLR7 (0.67) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016180695-A1 | NOVEL SULFONIMIDOYLPURINONE COMPOUNDS AND DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2016-11-17 | — | — | WO | disclosed |