Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 6/20 | 0.79 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18240011 | 0.92 | BCL2 (0.79) | BCL2BCL2L1 | |
| SCHEMBL1743243 | 0.88 | BCL2 (0.89) | BCL2BCL2L1 | |
| SCHEMBL1743443 | 0.88 | BCL2 (1.00) | BCL2BCL2L1 | |
| SCHEMBL1743246 | 0.86 | BCL2 (1.00) | BCL2BCL2L1 | |
| SCHEMBL2798924 | 0.86 | BCL2 (1.00) | BCL2BCL2L1 | |
| SCHEMBL1745756 | 0.80 | BCL2 (0.89) | BCL2BCL2L1 | |
| SCHEMBL1744369 | 0.80 | BCL2 (1.00) | BCL2BCL2L1 | |
| SCHEMBL19424991 | 0.79 | — | — | |
| SCHEMBL18240009 | 0.78 | BCL2 (1.00) | BCL2BCL2L1 | |
| SCHEMBL19424988 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3095784-A1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | AbbVie Inc. (US) | 2016-11-23 | — | — | EP | disclosed |