Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ASGR1 | P07306 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 4/20 | 0.30 |
| ▸ | CA12 | O43570 | 3/20 | 0.30 |
| ▸ | CA1 | P00915 | 3/20 | 0.30 |
| ▸ | CA2 | P00918 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10705909 | 0.82 | KMT2A (0.37) | KMT2ALMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL10526458 | 0.82 | KMT2A (0.37) | KMT2ALMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL2454869 | 0.80 | CA9 (0.34) | CA9CA12CA1CA2 | |
| SCHEMBL9050829 | 0.80 | CA9 (0.34) | CA9CA12CA1CA2 | |
| SCHEMBL7924602 | 0.80 | CA9 (0.34) | CA9CA12CA1CA2 | |
| SCHEMBL22729124 | 0.80 | CA9 (0.34) | CA9CA12CA1CA2 | |
| SCHEMBL12452164 | 0.77 | KMT2A (0.37) | KMT2AALDH1A1L3MBTL1ASGR1 | |
| SCHEMBL2835405 | 0.76 | CA12 (0.31) | CA9CA12CA1CA2 | |
| SCHEMBL2835403 | 0.76 | CA12 (0.31) | CA9CA12CA1CA2 | |
| SCHEMBL23969153 | 0.75 | NEU3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180180626-A1 | A METHOD FOR DEVELOPMENT OF RECOMBINANT PROTEINS WITH FINGERPRINT LIKE SIMILARITY TO THE REFERENCE PRODUCT | STC BIOLOGICS INC (US) | 2018-06-28 | — | — | US | disclosed |
| US-9868973-B2 | Method for optimizing post-translational modifications on recombinant proteins | STC BIOLOGICS, INC. (US) | 2018-01-16 | — | — | US | disclosed |
| US-20160340706-A1 | Method for Optimizing Post-Translational Modifications on Recombinant Proteins | STC BIOLOGICS, INC. | 2016-11-24 | — | — | US | disclosed |