SCHEMBL18245295

SCHEMBL18245295

COC(=O)[C@H]1CN(C)CC[C@H]1c1ccc2ccccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ SLC6A2 P23975 5/20 0.73
▸ SLC6A4 P31645 5/20 0.73
▸ SLC6A3 Q01959 5/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20942840 1.00 SLC6A2 (0.73) SLC6A2SLC6A4SLC6A3
SCHEMBL7812301 0.87 SLC6A2 (0.55) SLC6A2SLC6A4SLC6A3
SCHEMBL7086307 0.86 SLC6A2 (0.55) SLC6A2SLC6A4SLC6A3
SCHEMBL7086304 0.86 SLC6A2 (0.55) SLC6A2SLC6A4SLC6A3
SCHEMBL3467519 0.86 SLC6A2 (0.55) SLC6A2SLC6A4SLC6A3
SCHEMBL6923261 0.84 SLC6A2 (1.00) SLC6A2SLC6A4SLC6A3
SCHEMBL6923257 0.84 SLC6A2 (1.00) SLC6A2SLC6A4SLC6A3
SCHEMBL6829748 0.82 SLC6A2 (0.76) SLC6A2SLC6A4SLC6A3
SCHEMBL8602659 0.82 SLC6A2 (0.76) SLC6A2SLC6A4SLC6A3
SCHEMBL6829747 0.82 SLC6A2 (0.76) SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2568805-B1 A MEDICAL FLUID, A METHOD OF TREATMENT AND USE OF THE FLUID XVIVO PERFUSION AB (SE) 2019-05-01 — — EP claimed
US-20160354359-A1 COMPOSITION COMPRISING NOR-ADRENALINE AND A NET INHIBITOR FOR ADMINISTERING TO A BRAIN-DEAD, HEART-BEATING POTENTIAL ORGAN DONOR XVIVO PERFUSION AB (SE) 2016-12-08 — — US claimed
EP-2568805-B1 A MEDICAL FLUID, A METHOD OF TREATMENT AND USE OF THE FLUID XVIVO PERFUSION AB (SE) 2019-05-01 — — EP disclosed
US-10271540-B2 Medical fluid, a method of treatment and use of the fluid XVIVO PERFUSION AB (SE) 2019-04-30 — — US disclosed
US-20160354359-A1 COMPOSITION COMPRISING NOR-ADRENALINE AND A NET INHIBITOR FOR ADMINISTERING TO A BRAIN-DEAD, HEART-BEATING POTENTIAL ORGAN DONOR XVIVO PERFUSION AB (SE) 2016-12-08 — — US disclosed
US-20160338343-A1 MEDICAL FLUID, A METHOD OF TREATMENT AND USE OF THE FLUID XVIVO PERFUSION AB (SE) 2016-11-24 — — US disclosed
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