Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 16/20 | 0.41 |
| ▸ | CA2 | P00918 | 16/20 | 0.41 |
| ▸ | CA12 | O43570 | 14/20 | 0.41 |
| ▸ | CA9 | Q16790 | 14/20 | 0.41 |
| ▸ | CA4 | P22748 | 7/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1843154 | 0.96 | CA1 (0.44) | CA1CA2CA12CA9CA4 | |
| SCHEMBL2192099 | 0.91 | CA1 (0.42) | CA1CA2CA12CA9CA4 | |
| SCHEMBL1823312 | 0.90 | CA1 (0.46) | CA1CA2CA12CA9CA4 | |
| SCHEMBL1825530 | 0.87 | CA1 (0.46) | CA1CA2CA12CA9CA4 | |
| SCHEMBL1821791 | 0.85 | CA1 (0.43) | CA1CA2CA12CA9CA4 | |
| SCHEMBL12508192 | 0.83 | CA1 (0.49) | CA1CA2CA12CA9CA4 | |
| SCHEMBL2189446 | 0.82 | CA1 (0.43) | CA1CA2CA12CA9CA4 | |
| SCHEMBL1821765 | 0.82 | CA1 (0.50) | CA1CA2CA12CA9CA4 | |
| SCHEMBL2191155 | 0.82 | CA1 (0.52) | CA1CA2CA12CA9CA4 | |
| SCHEMBL1822875 | 0.81 | CA1 (0.44) | CA1CA2CA12CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060196-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-05-19 | — | — | WO | disclosed |