Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18249445 | 0.90 | UTS2R (0.47) | TSHRGAAUTS2RUSP2ALOX15 | |
| SCHEMBL15269465 | 0.83 | TSHR (0.49) | TSHRGAAUSP2ALOX15LMNA | |
| SCHEMBL20164283 | 0.81 | TSHR (0.50) | TSHRGAAUTS2RUSP2ALOX15 | |
| SCHEMBL18249485 | 0.81 | GAA (0.47) | TSHRGAAUTS2RLMNACYP1A2 | |
| SCHEMBL18249406 | 0.79 | TSHR (0.42) | TSHRLMNAALDH1A1CYP3A4DRD3 | |
| SCHEMBL18249427 | 0.77 | UTS2R (0.46) | TSHRGAAUTS2RUSP2ALOX15 | |
| SCHEMBL15233877 | 0.76 | TSHR (0.49) | TSHRGAAUSP2ALOX15LMNA | |
| SCHEMBL15269367 | 0.76 | USP2 (0.46) | TSHRGAAUTS2RUSP2ALOX15 | |
| SCHEMBL15269591 | 0.76 | USP2 (0.48) | TSHRGAAUTS2RUSP2ALOX15 | |
| SCHEMBL20164210 | 0.76 | GAA (0.70) | TSHRGAALMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016184884-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-11-24 | — | — | WO | disclosed |