Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27306644 | 1.00 | FFAR3 (0.78) | — | |
| Acetic Acid SCHEMBL27306643 | 1.00 | FFAR3 (0.78) | — | |
| Acetic Acid SCHEMBL28097492 | 0.94 | — | — | |
| Acetic Acid SCHEMBL29070664 | 0.94 | FFAR3 (0.88) | — | |
| Acetic Acid SCHEMBL11637781 | 0.94 | FFAR3 (0.88) | — | |
| Acetic Acid SCHEMBL27647072 | 0.94 | FFAR3 (0.88) | — | |
| Acetic Acid SCHEMBL27719132 | 0.94 | — | — | |
| Acetic Acid SCHEMBL3101179 | 0.94 | FFAR3 (0.88) | — | |
| Acetic Acid SCHEMBL866791 | 0.94 | — | — | |
| Acetic Acid SCHEMBL2916665 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3297678-B1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS LTD (IN) | 2021-07-07 | — | — | EP | claimed |
| US-10364269-B2 | Processes for the preparation of carfilzomib or pharmaceutically acceptable salts thereof | LAURUS LABS LIMITED (IN) | 2019-07-30 | — | — | US | claimed |
| US-20190085026-A1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | Laurus Labs Ltd. (IN) | 2019-03-21 | — | — | US | claimed |
| EP-3297678-A1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | Laurus Labs Private Limited (IN) | 2018-03-28 | — | — | EP | claimed |
| WO-2016185450-A1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS PRIVATE LIMITED (IN) | 2016-11-24 | — | — | WO | claimed |
| CN-1056699-A | Latent catalysts and cure-inhibited epoxy resin compositions and laminates made therefrom | DOW CHEMICAL CO (US) | 1991-12-04 | — | — | CN | claimed |
| EP-3297678-B1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS LTD (IN) | 2021-07-07 | — | — | EP | disclosed |
| US-10800809-B2 | Processes for the preparation of carfilzomib or pharmaceutically acceptable salts thereof | LAURUS LABS LIMITED (IN) | 2020-10-13 | — | — | US | disclosed |
| US-20190284231-A1 | PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS LIMITED (IN) | 2019-09-19 | — | — | US | disclosed |
| US-10364269-B2 | Processes for the preparation of carfilzomib or pharmaceutically acceptable salts thereof | LAURUS LABS LIMITED (IN) | 2019-07-30 | — | — | US | disclosed |
| US-20190085026-A1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | Laurus Labs Ltd. (IN) | 2019-03-21 | — | — | US | disclosed |
| CN-108051578-A | The nano-pore carried out by local potential measurement senses | 哈佛大学校长及研究员协会 | 2018-05-18 | — | — | CN | disclosed |
| EP-3297678-A1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | Laurus Labs Private Limited (IN) | 2018-03-28 | — | — | EP | disclosed |
| CN-1249772-A | Latent catalysts for epoxy curing systems | DOW CHEMICAL CO (US) | 2000-04-05 | — | — | CN | disclosed |
| CN-1050618-C | Latent Catalysts, Cure-inhibited epxoy resin compositions and laminates prepared therefrom | DOW CHEMICAL CO (US) | 2000-03-22 | — | — | CN | disclosed |
| CN-1050617-C | Latent catalysts, cure-inhibited epxoy resin compositions and laminates prepared therefrom | DOW CHEMICAL CO (US) | 2000-03-22 | — | — | CN | disclosed |
| CN-1035823-C | Process for preparing latent catalysts for curing epoxy resins | DOW CHEMICAL CO (US) | 1997-09-10 | — | — | CN | disclosed |
| CN-1118794-A | Latent Catalysts, Cure-inhibited epxoy resin compositions and laminates prepared therefrom | DOW CHEMICAL CO (US) | 1996-03-20 | — | — | CN | disclosed |
| CN-1118793-A | Latent catalysts, cure-inhibited epxoy resin compositions and laminates prepared therefrom | DOW CHEMICAL CO (US) | 1996-03-20 | — | — | CN | disclosed |
| CN-1056699-A | Latent catalysts and cure-inhibited epoxy resin compositions and laminates made therefrom | DOW CHEMICAL CO (US) | 1991-12-04 | — | — | CN | disclosed |