Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728089 | 1.00 | TSHR (0.59) | TSHRALDH1A1TDP1MMP3MMP9 | |
| Sulfuric Acid SCHEMBL1824227 | 0.95 | TSHR (0.54) | TSHRALDH1A1TDP1MMP3MMP9 | |
| SCHEMBL1824226 | 0.91 | TSHR (0.50) | TSHRALDH1A1TDP1MMP3MMP9 | |
| SCHEMBL14296911 | 0.86 | TSHR (0.62) | TSHRALDH1A1TDP1MMP3MMP9 | |
| SCHEMBL1723878 | 0.83 | TSHR (0.59) | TSHRALDH1A1TDP1MMP3MMP9 | |
| SCHEMBL1724880 | 0.83 | TSHR (0.59) | TSHRALDH1A1TDP1MMP3MMP9 | |
| SCHEMBL1723696 | 0.83 | TSHR (0.59) | TSHRALDH1A1TDP1MMP3MMP9 | |
| SCHEMBL14353631 | 0.83 | TSHR (0.59) | TSHRALDH1A1TDP1MMP3MMP9 | |
| SCHEMBL3631759 | 0.83 | TSHR (0.59) | TSHRALDH1A1TDP1MMP3MMP9 | |
| SCHEMBL29859252 | 0.83 | TSHR (0.59) | TSHRALDH1A1TDP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2498782-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | Pharmatrophix Inc. (US) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011060262-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | PHARMATROPHIX, INC. (US) | 2011-05-19 | — | — | WO | disclosed |