Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 8/20 | 0.67 |
| ▸ | ABL1 | P00519 | 6/20 | 0.67 |
| ▸ | SRC | P12931 | 6/20 | 0.67 |
| ▸ | EGFR | P00533 | 5/20 | 0.67 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.67 |
| ▸ | PRKDC | P78527 | 5/20 | 0.67 |
| ▸ | HCK | P08631 | 4/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.67 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.67 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.67 |
| ▸ | KDR | P35968 | 3/20 | 0.67 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.67 |
| ▸ | FYN | P06241 | 5/20 | 0.66 |
| ▸ | RET | P07949 | 4/20 | 0.66 |
| ▸ | YES1 | P07947 | 3/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24519592 | 0.86 | ABL1 (0.75) | MTORABL1SRCEGFRPIK3CD | |
| SCHEMBL27943343 | 0.86 | MTOR (0.71) | MTORABL1SRCEGFRPIK3CD | |
| SCHEMBL30405669 | 0.83 | MTOR (0.74) | MTORABL1SRCEGFRPIK3CD | |
| SCHEMBL20553355 | 0.83 | MTOR (0.74) | MTORABL1SRCEGFRPIK3CD | |
| SCHEMBL23917412 | 0.81 | ABL1 (1.00) | MTORABL1SRCEGFRPIK3CD | |
| SCHEMBL25113289 | 0.81 | MTOR (0.71) | MTORABL1SRCEGFRPIK3CD | |
| SCHEMBL18250089 | 0.80 | MTOR (1.00) | MTORABL1SRCEGFRPIK3CD | |
| SCHEMBL25113261 | 0.78 | PIK3C2B (0.55) | MTORABL1SRCEGFRPIK3CD | |
| SCHEMBL18258361 | 0.76 | SRC (1.00) | MTORABL1SRCEGFRPIK3CD | |
| SCHEMBL12265009 | 0.76 | EGFR (1.00) | MTORABL1SRCEGFRPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298015-A1 | COMPOUNDS | The University Court of the University of Edinburgh (GB) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016185160-A1 | COMPOUNDS | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2016-11-24 | — | — | WO | disclosed |