SCHEMBL18255446

SCHEMBL18255446

Cc1c(NC(=O)Oc2ccccc2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1

nearest known ligand 0.58

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 7/20 0.56
CNR2 P34972 6/20 0.56
PPARA Q07869 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18255445 0.87 CNR2 (0.62) CNR1CNR2PPARA
SCHEMBL31478271 0.84 CNR2 (0.58) CNR1CNR2PPARA
SCHEMBL18255458 0.84 CNR1 (0.60) CNR1CNR2PPARA
SCHEMBL18255448 0.81 CNR2 (0.56) CNR1CNR2PPARA
SCHEMBL18255407 0.81 CNR2 (0.61) CNR1CNR2PPARA
SCHEMBL18255429 0.80 CNR1 (0.63) CNR1CNR2
SCHEMBL18255457 0.78 CNR2 (0.55) CNR1CNR2PPARA
SCHEMBL18255367 0.78 CNR2 (0.70) CNR1CNR2PPARA
SCHEMBL675302 0.77 CNR1 (0.89) CNR1CNR2
SCHEMBL18255373 0.77 CNR1 (0.65) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016184310-A1 4-METHYL-1H-DIARYL PYRAZOLE DERIVATIVES AND USES AS DRUGS THEREOF 中国人民解放军军事医学科学院毒物药物研究所 2016-11-24 WO disclosed