SCHEMBL18256

SCHEMBL18256

CC(O)C(=O)Oc1ccc2ccccc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.54
MEN1 O00255 1/20 0.54
MAPT P10636 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
KDM4E B2RXH2 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ALDH1A1 P00352 1/20 0.49
HSD17B10 Q99714 1/20 0.49
RECQL P46063 1/20 0.48
UGT2B7 P16662 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2A6 P11509 1/20 0.47
PPARG P37231 2/20 0.46
PPARA Q07869 2/20 0.46
PTPN7 P35236 1/20 0.46
MMP1 P03956 2/20 0.45
MMP12 P39900 1/20 0.45
FABP7 O15540 1/20 0.44
FABP3 P05413 1/20 0.44
BCHE P06276 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10325206 1.00 KMT2A (0.54) KMT2AMEN1MAPTTDP1KDM4E
Ammonia Solution, Strong SCHEMBL2067052 0.98 KMT2A (0.53) KMT2AMEN1MAPTTDP1KDM4E
Hydrochloric Acid SCHEMBL7736403 0.98 KMT2A (0.53) KMT2AMEN1MAPTTDP1KDM4E
Phosphine SCHEMBL9464028 0.98 KMT2A (0.53) KMT2AMEN1MAPTTDP1KDM4E
Acetone SCHEMBL15224657 0.97 KMT2A (0.51) KMT2AMEN1MAPTTDP1KDM4E
Methoxymethane SCHEMBL11657047 0.97 KMT2A (0.51) KMT2AMEN1MAPTTDP1KDM4E
Toluene SCHEMBL11299289 0.92 KMT2A (0.51) KMT2AMEN1MAPTTDP1KDM4E
Phenol SCHEMBL8570756 0.92 KMT2A (0.51) KMT2AMEN1MAPTTDP1KDM4E
Pyrrole SCHEMBL4620322 0.91 KMT2A (0.46) KMT2AMEN1MAPTTDP1KDM4E
SCHEMBL9334467 0.91 KMT2A (0.46) KMT2AMEN1MAPTTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5487 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12012497-B2 Recovered carbon black and composite material comprising said recovered carbon black BLACK BEAR CARBON B.V. (NL) 2024-06-18 US claimed
WO-2024124117-A1 EMULSION-BASED THICK-FILM ANTIFOULING COATING FOR HIGHLY SENSITIVE ELECTROCHEMICAL SENSING PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-06-13 WO claimed
WO-2024107917-A1 SYNTHETIC ENAMEL AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2024-05-23 WO claimed
US-20240082830-A1 TRIARYL BORANE CATALYSTS AND METHOD FOR SELECTIVE HYDROSILYLATION OF ESTERS AND LACTONES USING SAID CATALYSTS ALDEXCHEM KFT. (HU) 2024-03-14 US claimed
EP-3355709-B1 CHEWING GUMS CONTAINING ALLULOSE WRIGLEY W M JUN CO (US) 2024-02-21 EP claimed
EP-3781544-B1 PROCESS FOR THE PREPARATION OF ILOPROST EUROAPI HUNGARY LLC (HU) 2023-11-08 EP claimed
EP-4263560-A1 TRIARYL BORANE CATALYSTS AND METHOD FOR SELECTIVE HYDROSILYLATION OF ESTERS AND LACTONES USING SAID CATALYSTS AldexChem Kft. (HU) 2023-10-25 EP claimed
CN-111989318-B Novel synthesis method of DHPV 医疗法人圣光医疗财团 2023-04-04 CN claimed
US-11535580-B2 Process for the preparation of iloprost CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) 2022-12-27 US claimed
CN-111234069-B Magnesium/titanium-containing solid catalyst component, preparation method thereof, olefin polymerization catalyst and application thereof 中国石油化工股份有限公司 2022-10-21 CN claimed
EP-0043446-A1 Intermediates of 13-thia-prostaglandin, their preparation and application to the synthesis of 13-thia-prostaglandin derivatives MERCK PATENT GmbH (DE) 1982-01-13 EP claimed
US-4231945-A BACTERICIDES SCHERING CORPORATION (US) 1980-11-04 US claimed
US-4217360-A LUTEOLYTIC SCHERING AKTIENGESELLSCHAFT (DE) 1980-08-12 US claimed
US-4212860-A COUPLING THE PENTOFURANOSYL ONTO THE PROTECTED CYCLITOL SCHERING CORPORATION (US) 1980-07-15 US claimed
EP-0008077-A2 Prostaglandin derivatives with a delta-2-PGF2 structure or a delta-2-PGE2 structure, process for their preparation and their use as medicaments HOECHST AKTIENGESELLSCHAFT (DE) 1980-02-20 EP claimed
EP-0002215-A1 Bicycloalkenyl-prostaglandines, their preparation and their application as therapeutics BAYER AG (DE) 1979-06-13 EP claimed
EP-0000710-A1 Prostaglandin analogues, process for their preparation and their use as medicaments BAYER AG (DE) 1979-02-21 EP claimed
US-4107427-A REDUCTION OF A LACTONE TO A LACTOL INTERMEDIATE THE UPJOHN COMPANY (US) 1978-08-15 US claimed
US-4033949-A Analogs of thromboxane B2 and processes for their synthesis THE UPJOHN COMPANY (US) 1977-07-05 US claimed
US-3970692-A Process for the preparation of prostaglandin F2.sub.α and the analogs thereof SCHERING AKTIENGESELLSCHAFT (DT) 1976-07-20 US claimed