Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.43 |
| ▸ | CA2 | P00918 | 12/20 | 0.43 |
| ▸ | CA12 | O43570 | 11/20 | 0.41 |
| ▸ | CA9 | Q16790 | 11/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.41 |
| ▸ | BTK | Q06187 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827664 | 0.88 | CA1 (0.47) | CA1CA2CA12CA9BTK | |
| SCHEMBL1822440 | 0.76 | CA1 (0.46) | CA1CA2CA12CA9BTK | |
| SCHEMBL12318910 | 0.76 | CA1 (0.48) | CA1CA2CA12CA9CA4 | |
| SCHEMBL1135310 | 0.74 | CA1 (0.57) | CA1CA2CA12CA9CA4 | |
| SCHEMBL1823699 | 0.74 | CA1 (0.49) | CA1CA2CA12CA9BTK | |
| SCHEMBL1821036 | 0.74 | CA1 (0.46) | CA1CA2CA12CA9CA4 | |
| SCHEMBL1826281 | 0.74 | CA1 (0.47) | CA1CA2CA12CA9BTK | |
| SCHEMBL1824434 | 0.74 | FFAR4 (0.57) | CA1CA2CA12CA9FFAR4 | |
| SCHEMBL2409244 | 0.74 | CA1 (0.43) | CA1CA2CA12CA9CA4 | |
| SCHEMBL1815618 | 0.73 | TOP2A (0.49) | CA1CA2CA12CA9FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060199-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-05-19 | — | — | WO | disclosed |