Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.65 |
| ▸ | BRD2 | P25440 | 6/20 | 0.65 |
| ▸ | BRD3 | Q15059 | 6/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.65 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.65 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CCL2 | P13500 | 1/20 | 0.65 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.65 |
| ▸ | TACR1 | P25103 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.65 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.65 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.65 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.65 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18249916 | 0.81 | BRD4 (0.65) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL17051097 | 0.81 | BRD4 (0.66) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL12098810 | 0.79 | BRD4 (1.00) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL29376121 | 0.79 | BRD4 (1.00) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL29366680 | 0.79 | BRD4 (1.00) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL1904423 | 0.79 | BRD4 (1.00) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL1906755 | 0.79 | BRD4 (1.00) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL18258270 | 0.79 | BRD4 (0.64) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL30014518 | 0.78 | BRD4 (0.98) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL20830846 | 0.78 | BRD4 (0.64) | BRD4BRD2BRD3CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016186453-A1 | QUINOLINE DERIVATIVES AS BROMODOMAIN INHIBITORS | KAINOS MEDICINE, INC. (KR) | 2016-11-24 | — | — | WO | disclosed |