SCHEMBL1825889

SCHEMBL1825889

COC(=O)Cc1cc(NC(=O)C(F)(F)F)ccc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2.N#CCc1cccc([N+](=O)[O-])c1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 7/20 0.39
CA2 P00918 7/20 0.39
CA12 O43570 5/20 0.37
CA9 Q16790 5/20 0.37
CA4 P22748 2/20 0.37
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1823940 0.86 CA1 (0.49) CA1CA2CA12CA9CA4
SCHEMBL1823072 0.79 CA1 (0.47) CA1CA2CA12CA9CA4
SCHEMBL12419368 0.77 CA1 (0.53) CA1CA2CA12CA9CA4
SCHEMBL1823070 0.76 CA1 (0.40) CA1CA2CA12CA9CA4
SCHEMBL1824452 0.76 CA1 (0.48) CA1CA2CA12CA9CA4
SCHEMBL1821765 0.74 CA1 (0.50) CA1CA2CA12CA9CA4
SCHEMBL2191155 0.74 CA1 (0.52) CA1CA2CA12CA9CA4
SCHEMBL12508192 0.74 CA1 (0.49) CA1CA2CA12CA9CA4
SCHEMBL1822786 0.74 CA1 (0.46) CA1CA2CA12CA9CA4
SCHEMBL1827629 0.74 CA1 (0.53) CA1CA2CA12CA9CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011060196-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2011-05-19 WO disclosed