SCHEMBL18262000

SCHEMBL18262000

NC(=O)NC1CCCCC1.NC(=O)NC1CCCCC1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 8/20 0.64
NPC1 O15118 4/20 0.64
SMN1; SMN2 Q16637 4/20 0.64
RAB9A P51151 3/20 0.64
ALDH1A1 P00352 2/20 0.64
CYP3A4 P08684 2/20 0.64
MAPT P10636 1/20 0.64
KDM4E B2RXH2 1/20 0.64
EPHX2 P34913 1/20 0.64
MMP2 P08253 3/20 0.52
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA9 Q16790 2/20 0.52
MMP8 P22894 1/20 0.52
MMP1 P03956 1/20 0.52
MMP3 P08254 1/20 0.52
MAPK1 P28482 1/20 0.52
DUSP3 P51452 1/20 0.52
PTPN5 P54829 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1757034 1.00 EPHX1 (0.64) EPHX1NPC1SMN1; SMN2RAB9AALDH1A1
SCHEMBL1756853 1.00 EPHX1 (0.64) EPHX1NPC1SMN1; SMN2RAB9AALDH1A1
SCHEMBL78650 1.00 EPHX1 (0.64) EPHX1NPC1SMN1; SMN2RAB9AALDH1A1
Hydrochloric Acid SCHEMBL28098897 0.97 EPHX1 (0.61) EPHX1NPC1SMN1; SMN2RAB9AALDH1A1
SCHEMBL966688 0.97
Hydrochloric Acid SCHEMBL27740151 0.95 EPHX1 (0.56) EPHX1NPC1SMN1; SMN2RAB9AALDH1A1
Urea SCHEMBL28834423 0.95 EPHX1 (0.56) EPHX1NPC1SMN1; SMN2RAB9AALDH1A1
SCHEMBL688635 0.92
SCHEMBL15277766 0.91 EPHX1 (0.74) EPHX1NPC1SMN1; SMN2RAB9AALDH1A1
Hydrochloric Acid SCHEMBL27565992 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016188988-A1 COSMETIC COMPOSITIONS COMPRISING E/Z-2-BENZYLINDENE-5,6-DIMETHOXY-3,3-DIMETHYLINDAN-1-ONE SYMRISE AG (DE) 2016-12-01 WO disclosed
WO-2016189024-A1 COSMETIC COMPOSITIONS COMPRISING SCLAREOLIDE SYMRISE AG (DE) 2016-12-01 WO disclosed
WO-2016189046-A1 COSMETIC COMPOSITIONS COMPRISING PURPLE CONEFLOWER PRESSED JUICE SYMRISE AG (DE) 2016-12-01 WO disclosed
WO-2016189038-A1 COSMETIC COMPOSITIONS COMPRISING GINGER ROOT EXTRACTS SYMRISE AG (DE) 2016-12-01 WO disclosed