SCHEMBL18262007

SCHEMBL18262007

CC(C)(C)OC(=O)NCC=CCNC(=O)OC(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.50
MEN1 O00255 1/20 0.47
GAA P10253 1/20 0.47
KMT2A Q03164 1/20 0.47
CTSK P43235 3/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
CA1 P00915 4/20 0.41
CA2 P00918 4/20 0.41
CA12 O43570 2/20 0.41
CA9 Q16790 2/20 0.41
EPHX1 P07099 1/20 0.41
CA7 P43166 1/20 0.40
PTPN11 Q06124 1/20 0.40
IDO1 P14902 1/20 0.39
NAMPT P43490 1/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18262010 1.00 TDP1 (0.50) TDP1MEN1GAAKMT2ACTSK
SCHEMBL18487257 1.00 TDP1 (0.50) TDP1MEN1GAAKMT2ACTSK
SCHEMBL661594 0.92 TDP1 (0.49) TDP1MEN1GAAKMT2ACTSK
SCHEMBL20437999 0.92 TDP1 (0.44) TDP1MEN1GAAKMT2ACTSK
SCHEMBL28060706 0.92 TDP1 (0.44) TDP1MEN1GAAKMT2ACTSK
SCHEMBL18262802 0.92 MEN1 (0.46) TDP1MEN1GAAKMT2ACTSK
SCHEMBL19420087 0.92 TDP1 (0.44) TDP1MEN1GAAKMT2ACTSK
SCHEMBL661593 0.92 TDP1 (0.49) TDP1MEN1GAAKMT2ACTSK
SCHEMBL13092290 0.92 TDP1 (0.44) TDP1MEN1GAAKMT2ACTSK
SCHEMBL18294565 0.92 TDP1 (0.49) TDP1MEN1GAAKMT2ACTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10563009-B2 Process to produce a polyolefin reactive telechelic pre-polymer DOW GLOBAL TECHNOLOGIES LLC (US) 2020-02-18 US disclosed
US-20180162998-A1 A POLYOLEFIN REACTIVE TELECHELIC PRE-POLYMER DOW GLOBAL TECHNOLOGIES LLC (US) 2018-06-14 US disclosed
US-20180134840-A1 PROCESS TO PRODUCE A POLYOLEFIN REACTIVE TELECHELIC PRE-POLYMER DOW GLOBAL TECHNOLOGIES LLC (US) 2018-05-17 US disclosed
EP-3303443-A1 A PROCESS TO PRODUCE A POLYOLEFIN REACTIVE TELECHELIC PRE-POLYMER Dow Global Technologies LLC (US) 2018-04-11 EP disclosed
EP-3303442-A1 A POLYOLEFIN REACTIVE TELECHELIC PRE-POLYMER Dow Global Technologies LLC (US) 2018-04-11 EP disclosed
WO-2016191688-A1 A PROCESS TO PRODUCE A POLYOLEFIN REACTIVE TELECHELIC PRE-POLYMER DOW GLOBAL TECHNOLOGIES LLC (US) 2016-12-01 WO disclosed
WO-2016191692-A1 A POLYOLEFIN REACTIVE TELECHELIC PRE-POLYMER DOW GLOBAL TECHNOLOGIES LLC (US) 2016-12-01 WO disclosed