SCHEMBL1826288

SCHEMBL1826288

CC(C)(C)C[SiH2]Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3207087 0.67 TSHR (0.36)
SCHEMBL2271520 0.65
SCHEMBL8418183 0.64
SCHEMBL1826167 0.61
SCHEMBL14156300 0.61
SCHEMBL23700991 0.61
SCHEMBL23701336 0.61
SCHEMBL2443734 0.61
SCHEMBL28482905 0.61
Chloromethane SCHEMBL11586703 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2134696-A2 PROCESSES FOR THE PREPARATION OF STATINS, PARTICULARLY ROSUVASTATIN, AND INTERMEDIATES FOR THE PREPARATION THEREOF Lek Pharmaceuticals D.D. (SI) 2009-12-23 EP claimed
WO-2008119810-A2 PROCESSES FOR THE PREPARATION OF STATINS, PARTICULARLY ROSUVASTATIN, AND INTERMEDIATES FOR THE PREPARATION THEREOF LEK PHARMACEUTICALS D.D. (SI) 2008-10-09 WO claimed
WO-2001060932-A1 ANTIFOULING PAINT COMPOSITION J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2001-08-23 WO claimed
WO-1996012723-A1 PROCESS FOR PREPARING ALKYLSILYL OR ARYLSILYL ETHERS FMC CORPORATION (US) 1996-05-02 WO claimed
US-5493044-A Process for preparing alkylsilyl or arylsilyl ethers FMC CORPORATION (US) 1996-02-20 US claimed
US-5132376-A Process for selective removal of dimeric species from phenolic polymers OCG MICROELECTRONIC MATERIALS, INC. (US) 1992-07-21 US claimed
JP-2157286-A None JP disclosed
JP-4036289-A None JP disclosed
JP-63316791-A None JP disclosed
CN-122029171-A Small molecule inhibitors of KRAS proteins 默沙东有限责任公司 2026-05-12 CN disclosed
US-20260041661-A1 THREE-COMPONENT PRODRUG, PHARMACEUTICAL COMPOSITION THEREOF, AND MEDICAL USE THEREOF J2H BIOTECH INC. (KR) 2026-02-12 US disclosed
CN-116622005-B Polymer prodrug compound and preparation method thereof, and polymer prodrug micelle and preparation method thereof 成都中医药大学 2025-02-14 CN disclosed
US-20240327444-A1 Method for Purifying Nucleotides, Device for Purifying Nucleotides, Hy-Drophobic Reagent, and Hydrophobic Substrate JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2024-10-03 US disclosed
EP-0405560-A2 Preparation of tertiary-hydrocarbylsilyl compounds Dow Corning Toray Silicone Company, Limited (JP) 1991-01-02 EP disclosed
JP-H02157286-A PRODUCTION OF CHLORINATED SILICON COMPOUND SHIN ETSU CHEM CO LTD 1990-06-18 JP disclosed
US-4879389-A HYDROGENATION CATALYSTS ACHIWA KAZUO (JP) 1989-11-07 US disclosed
JP-S63316791-A PRODUCTION OF CHLORINATED SILICON COMPOUND SHIN ETSU CHEM CO LTD 1988-12-26 JP disclosed
US-4774347-A HYDROGENATION OF CHLOROALKANE WITH HYDROGEN CONTAINING SILANE DOW CORNING CORPORATION (US) 1988-09-27 US disclosed
EP-0251164-A2 New chiral phosphinopyrrolidine compounds and their use for asymetric synthesis of optically active compounds Achiwa, Kazuo (JP) 1988-01-07 EP disclosed
US-4324689-A High carbon content chromatographic packing and method for making same SHAH RAMESH M 1982-04-13 US disclosed