SCHEMBL18265015

SCHEMBL18265015

CCOc1ccc(Cc2cc(C3OC(CO)C(C)C(O)C3OC(C)=O)ccc2Cl)cc1

nearest known ligand 0.68

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 19/20 0.68
SLC5A1 P13866 11/20 0.68
ADRA2A P08913 1/20 0.68
SLC5A11 Q8WWX8 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18265403 0.94 SLC5A2 (0.72) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL18264999 0.93 SLC5A2 (0.71) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL18264993 0.93 SLC5A2 (0.65) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL15033244 0.93 SLC5A2 (0.65) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL17189290 0.93 SLC5A2 (0.76) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL18265390 0.91 SLC5A2 (0.73) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL18265396 0.90 SLC5A2 (0.78) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL18265370 0.90 SLC5A2 (0.68) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL15037575 0.90 SLC5A2 (0.68) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL18573750 0.90 SLC5A2 (0.76) SLC5A2SLC5A1ADRA2ASLC5A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170057989-A1 PHENYL C-GLUCOSIDE DERIVATIVE CONTAINING DEOXYGLUCOSE STRUCTURE, PREPARATION METHOD AND USE THEREOF TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH (CN) 2017-03-02 US disclosed
US-9505734-B2 Phenyl C-glucoside derivative containing deoxyglucose structure, preparation method and use thereof TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH (CN) 2016-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170057989-A1 PHENYL C-GLUCOSIDE DERIVATIVE CONTAINING DEOXYGLUCOSE STRUCTURE, PREPARATION METHOD AND USE THEREOF GCG, SLC5A1, DPP7 SLC5A2 6/4885SLC5A1 2/4885ADRA2A 3071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.