Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 4/20 | 0.55 |
| ▸ | MERTK | Q12866 | 4/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 16/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14736449 | 0.92 | AXL (0.66) | AXLMERTKPIK3CD | |
| SCHEMBL29836177 | 0.92 | AXL (0.66) | AXLMERTKPIK3CD | |
| SCHEMBL29836190 | 0.90 | PIK3CD (0.57) | AXLMERTKPIK3CD | |
| SCHEMBL14736740 | 0.90 | PIK3CD (0.57) | AXLMERTKPIK3CD | |
| SCHEMBL14736812 | 0.89 | PIK3CD (0.54) | AXLMERTKPIK3CD | |
| SCHEMBL14736759 | 0.89 | PIK3CD (0.66) | AXLMERTKPIK3CD | |
| SCHEMBL31367090 | 0.89 | PIK3CD (0.54) | AXLMERTKPIK3CD | |
| SCHEMBL14736676 | 0.89 | PIK3CD (0.66) | AXLMERTKPIK3CD | |
| SCHEMBL21408101 | 0.89 | PIK3CD (0.66) | AXLMERTKPIK3CD | |
| SCHEMBL29836217 | 0.89 | PIK3CD (0.66) | AXLMERTKPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751109-B1 | HETEROCYCLYLAMINES AS PI3K INHIBITORS | INCYTE HOLDINGS CORP (US) | 2016-11-30 | — | — | EP | disclosed |