Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 18/20 | 0.48 |
| ▸ | MAPT | P10636 | 10/20 | 0.48 |
| ▸ | GSK3A | P49840 | 8/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2715129 | 0.95 | GSK3B (0.48) | GSK3BMAPTGSK3AABL1ACACB | |
| SCHEMBL2714930 | 0.85 | GSK3B (0.47) | GSK3BMAPTGSK3AABL1ACACB | |
| SCHEMBL18266756 | 0.84 | ABL1 (0.43) | ABL1ACACB | |
| SCHEMBL18266845 | 0.84 | GSK3B (0.49) | GSK3BMAPTGSK3A | |
| SCHEMBL2715936 | 0.84 | GSK3B (0.44) | GSK3BMAPTGSK3AACACB | |
| SCHEMBL2716280 | 0.83 | MAPT (0.56) | GSK3BMAPTACACB | |
| SCHEMBL18266576 | 0.82 | GSK3B (0.48) | GSK3BMAPTGSK3AACACB | |
| SCHEMBL18266823 | 0.81 | GSK3B (0.48) | GSK3BMAPTGSK3AACACB | |
| SCHEMBL2717273 | 0.79 | GSK3B (0.54) | GSK3BMAPTGSK3A | |
| SCHEMBL2714481 | 0.79 | ABL1 (0.43) | ABL1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2630122-B1 | ARYLAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC (JP) | 2016-11-30 | — | — | EP | disclosed |