Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18267223 | 0.93 | PDK2 (0.49) | PDK2BRD4DHODHTNKSCYP1A2 | |
| SCHEMBL17206440 | 0.88 | PDK2 (0.45) | PDK2BRD4DHODHTNKSCYP1A2 | |
| SCHEMBL17206415 | 0.86 | PDK2 (0.44) | PDK2BRD4DHODHBACE1PRMT5 | |
| SCHEMBL14065151 | 0.85 | PDK2 (0.56) | PDK2TNKSCYP1A2CYP2D6CYP19A1 | |
| SCHEMBL17426592 | 0.84 | PDK2 (0.49) | PDK2BRD4DHODHCYP1A2CYP2D6 | |
| SCHEMBL17206476 | 0.84 | KDM4E (0.45) | PDK2BRD4DHODHCYP1A2PIK3CD | |
| SCHEMBL17206425 | 0.83 | PDK2 (0.44) | PDK2BRD4DHODHCYP1A2KDM4E | |
| SCHEMBL23996404 | 0.82 | PDK2 (0.43) | PDK2TNKSCYP1A2CYP2D6CYP19A1 | |
| SCHEMBL17206419 | 0.82 | PDK2 (0.43) | PDK2BRD4DHODHKDM4EPRMT5 | |
| SCHEMBL17206416 | 0.82 | PDK2 (0.40) | PDK2BRD4KDM4EPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9893305-B2 | Indenotriphenylene-based iridium complexes for organic electroluminescence device | UDC IRELAND LIMITED (IE) | 2018-02-13 | — | — | US | disclosed |
| US-9893305-B2 | Indenotriphenylene-based iridium complexes for organic electroluminescence device | UDC IRELAND LIMITED (IE) | 2018-02-13 | — | — | US | disclosed |
| US-20160351835-A1 | INDENOTRIPHENYLENE-BASED IRIDIUM COMPLEXES FOR ORGANIC ELECTROLUMINESCENCE DEVICE | UDC IRELAND LIMITED (IE) | 2016-12-01 | — | — | US | disclosed |
| US-20160351835-A1 | INDENOTRIPHENYLENE-BASED IRIDIUM COMPLEXES FOR ORGANIC ELECTROLUMINESCENCE DEVICE | UDC IRELAND LIMITED (IE) | 2016-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160351835-A1 | INDENOTRIPHENYLENE-BASED IRIDIUM COMPLEXES FOR ORGANIC ELECTROLUMINESCENCE DEVICE | CHRM1, IDO1, CCNE2 | PDK2 806/4885BRD4 81/4885DHODH 1907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.