SCHEMBL1826792

SCHEMBL1826792

N=C(N)COC(=O)Cc1cc(N)ccc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 12/20 0.44
CA2 P00918 12/20 0.44
CA12 O43570 11/20 0.44
CA9 Q16790 11/20 0.44
CA4 P22748 7/20 0.44
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37
PRSS3 P35030 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1825210 0.89 CA1 (0.46) CA1CA2CA12CA9CA4
SCHEMBL12508710 0.88 CA1 (0.48) CA1CA2CA12CA9CA4
SCHEMBL2195056 0.86 CA1 (0.51) CA1CA2CA12CA9CA4
SCHEMBL12508716 0.85 CA1 (0.46) CA1CA2CA12CA9CA4
SCHEMBL2192496 0.85 CA1 (0.44) CA1CA2CA12CA9CA4
SCHEMBL2192485 0.85 CA1 (0.44) CA1CA2CA12CA9CA4
SCHEMBL1821803 0.85 CA1 (0.51) CA1CA2CA12CA9CA4
SCHEMBL1819654 0.84 CA1 (0.45) CA1CA2CA12CA9CA4
SCHEMBL1819515 0.84 CA1 (0.52) CA1CA2CA12CA9CA4
SCHEMBL2193159 0.83 CA1 (0.52) CA1CA2CA12CA9CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011060196-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2011-05-19 WO disclosed