Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.79 |
| ▸ | PKM | P14618 | 2/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | ABL1 | P00519 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | IDE | P14735 | 1/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.79 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 3/20 | 0.62 |
| ▸ | CA1 | P00915 | 3/20 | 0.62 |
| ▸ | CA2 | P00918 | 3/20 | 0.62 |
| ▸ | CA9 | Q16790 | 3/20 | 0.62 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.57 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.57 |
| ▸ | HLCS | P50747 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9174298 | 1.00 | TDP1 (0.79) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL12606268 | 0.98 | TDP1 (0.79) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL16913029 | 0.97 | TDP1 (0.77) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL565248 | 0.97 | TDP1 (0.77) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL22975316 | 0.97 | TDP1 (0.77) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL25417015 | 0.97 | TDP1 (0.77) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL10171661 | 0.97 | TDP1 (0.77) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL565479 | 0.97 | TDP1 (0.77) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL12551857 | 0.97 | TDP1 (0.77) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL383254 | 0.97 | TDP1 (0.77) | TDP1PKMMEN1ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160346409-A1 | TARGETED MOLECULAR IMAGING CONTRAST AGENTS | UNIV MCMASTER (CA) | 2016-12-01 | — | — | US | disclosed |