Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1957140 | 0.89 | BCL2 (0.78) | BCL2 | |
| SCHEMBL19425129 | 0.84 | BCL2 (0.60) | BCL2 | |
| SCHEMBL1956093 | 0.83 | BCL2 (0.80) | BCL2 | |
| SCHEMBL19424930 | 0.79 | BCL2 (0.61) | BCL2 | |
| SCHEMBL19424732 | 0.78 | BCL2 (0.88) | BCL2 | |
| SCHEMBL1743045 | 0.78 | BCL2 (0.75) | BCL2 | |
| SCHEMBL1743338 | 0.78 | BCL2 (0.76) | BCL2 | |
| SCHEMBL19424955 | 0.77 | BCL2 (0.78) | BCL2 | |
| SCHEMBL1702539 | 0.77 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1956155 | 0.77 | BCL2 (0.87) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3101019-A1 | SULFONAMIDE DERIVATIVES AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES | AbbVie Inc. (US) | 2016-12-07 | — | — | EP | disclosed |