Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 3/20 | 0.67 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1957716 | 0.89 | BCL2 (0.74) | BCL2ADRA1DDRD3SLC6A3TMEM97 | |
| SCHEMBL2505525 | 0.86 | BCL2 (0.72) | BCL2ADRA1DDRD3SLC6A3TMEM97 | |
| SCHEMBL18274748 | 0.84 | BCL2 (0.69) | BCL2 | |
| SCHEMBL1955358 | 0.81 | BCL2 (0.86) | BCL2ADRA1DDRD3SLC6A3TMEM97 | |
| SCHEMBL30467960 | 0.80 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1810749 | 0.80 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1955269 | 0.80 | BCL2 (0.87) | BCL2 | |
| SCHEMBL19419660 | 0.78 | BCL2 (0.72) | BCL2ADRA1DDRD3SLC6A3TMEM97 | |
| SCHEMBL2505947 | 0.78 | BCL2 (0.85) | BCL2ADRA1DDRD3SLC6A3TMEM97 | |
| SCHEMBL1955256 | 0.77 | BCL2 (0.74) | BCL2ADRA1DDRD3SLC6A3TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3101019-A1 | SULFONAMIDE DERIVATIVES AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES | AbbVie Inc. (US) | 2016-12-07 | — | — | EP | disclosed |