Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18285508 | 1.00 | BTK (1.00) | BTK | |
| SCHEMBL18285509 | 1.00 | BTK (1.00) | BTK | |
| SCHEMBL20239015 | 0.92 | BTK (0.85) | BTK | |
| SCHEMBL20239011 | 0.92 | BTK (0.85) | BTK | |
| SCHEMBL20239013 | 0.92 | BTK (0.85) | BTK | |
| SCHEMBL18285568 | 0.91 | BTK (0.86) | BTK | |
| SCHEMBL18285567 | 0.91 | BTK (0.86) | BTK | |
| SCHEMBL18285570 | 0.91 | BTK (0.86) | BTK | |
| SCHEMBL29214033 | 0.91 | BTK (0.89) | BTK | |
| SCHEMBL20239008 | 0.89 | BTK (1.00) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303334-A1 | TYROSINE KINASE INHIBITORS | Principia Biopharma Inc. (US) | 2018-04-11 | — | — | EP | claimed |
| WO-2016196840-A1 | TYROSINE KINASE INHIBITORS | PRINCIPIA BIOPHARMA INC. (US) | 2016-12-08 | — | — | WO | claimed |
| EP-3303334-A1 | TYROSINE KINASE INHIBITORS | Principia Biopharma Inc. (US) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016196840-A1 | TYROSINE KINASE INHIBITORS | PRINCIPIA BIOPHARMA INC. (US) | 2016-12-08 | — | — | WO | disclosed |