Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1153493 | 0.84 | KDM4E (0.61) | KDM4ELMNAMAPK1SLC6A2TAAR1 | |
| SCHEMBL8540631 | 0.84 | KDM4E (0.61) | KDM4ELMNAMAPK1SLC6A2TAAR1 | |
| SCHEMBL1153491 | 0.84 | KDM4E (0.61) | KDM4ELMNAMAPK1SLC6A2TAAR1 | |
| Hydrochloric Acid SCHEMBL4524323 | 0.82 | KDM4E (0.59) | KDM4ELMNAMAPK1SLC6A2TAAR1 | |
| Water SCHEMBL11513174 | 0.82 | KDM4E (0.59) | KDM4ELMNAMAPK1SLC6A2TAAR1 | |
| SCHEMBL1234677 | 0.81 | KDM4E (0.58) | KDM4ELMNAMAPK1SLC6A2TAAR1 | |
| SCHEMBL3843513 | 0.79 | SLC6A2 (0.58) | KDM4ELMNAMAPK1SLC6A2TAAR1 | |
| SCHEMBL10253191 | 0.79 | SLC6A2 (0.58) | KDM4ELMNAMAPK1SLC6A2TAAR1 | |
| SCHEMBL5675489 | 0.79 | KDM4E (0.66) | KDM4ELMNAMAPK1SLC6A2TAAR1 | |
| SCHEMBL14038762 | 0.79 | SLC6A2 (0.58) | KDM4ELMNAMAPK1SLC6A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318126-A2 | WATER PURIFICATION MEMBRANES WITH IMPROVED FOULING RESISTANCE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010006196-A2 | WATER PURIFICATION MEMBRANES WITH IMPROVED FOULING RESISTANCE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-01-14 | — | — | WO | disclosed |