Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 3/20 | 0.54 |
| ▸ | CSF1R | P07333 | 3/20 | 0.52 |
| ▸ | CCNC | P24863 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 10/20 | 0.45 |
| ▸ | CDK9 | P50750 | 10/20 | 0.45 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12065009 | 1.00 | FYN (0.54) | FYNCSF1RCCNCCDK8CCNT1 | |
| SCHEMBL12056838 | 1.00 | FYN (0.54) | FYNCSF1RCCNCCDK8CCNT1 | |
| SCHEMBL12056828 | 0.93 | CSF1R (0.51) | FYNCSF1RCCNCCDK8CCNT1 | |
| SCHEMBL12056844 | 0.93 | CSF1R (0.51) | FYNCSF1RCCNCCDK8CCNT1 | |
| SCHEMBL18286646 | 0.93 | CSF1R (0.51) | FYNCSF1RCCNCCDK8CCNT1 | |
| SCHEMBL12056818 | 0.93 | FYN (0.55) | FYNCSF1RCCNCCDK8CCNT1 | |
| SCHEMBL12056775 | 0.93 | FYN (0.55) | FYNCSF1RCCNCCDK8CCNT1 | |
| SCHEMBL12056814 | 0.93 | CCNT1 (0.52) | FYNCSF1RCCNCCDK8CCNT1 | |
| SCHEMBL24411077 | 0.92 | CCNC (0.58) | FYNCSF1RCCNCCDK8CCNT1 | |
| SCHEMBL12056766 | 0.92 | CCNC (0.58) | FYNCSF1RCCNCCDK8CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022098808-A1 | THERAPEUTIC AGENTS FOR TREATING HEPATOCELLULAR CARCINOMA | ARIA PHARMACEUTICALS, INC. (US) | 2022-05-12 | — | — | WO | disclosed |
| EP-1569917-B1 | PYRAZINE-BASED TUBULIN INHIBITORS | YM BIOSCIENCES AUSTRALIA PTY (AU) | 2016-12-07 | — | — | EP | disclosed |