SCHEMBL182880

SCHEMBL182880

N#COC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17729877 1.00
SCHEMBL1741427 0.85
SCHEMBL30272073 0.76
SCHEMBL30016657 0.72
SCHEMBL8741767 0.67
SCHEMBL11591921 0.64
SCHEMBL13506702 0.61
SCHEMBL15021322 0.61
SCHEMBL3948679 0.61
SCHEMBL9934314 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4396259-B1 COMPOSITION MERCK PATENT GMBH (DE) 2026-02-04 EP claimed
US-20240352181-A1 COMPOSITION MERCK PATENT GMBH (DE) 2024-10-24 US claimed
EP-4396259-A1 COMPOSITION Merck Patent GmbH (DE) 2024-07-10 EP claimed
WO-2023031073-A1 COMPOSITION MERCK PATENT GMBH (DE) 2023-03-09 WO claimed
CN-111656792-B Polycycloolefin monomers as optical materials and catalysts activated by compounds capable of generating photoacid 住友电木株式会社 2022-03-15 CN claimed
EP-3077008-A1 BIOREVERSABLE PROMOIETIES FOR NITROGEN-CONTAINING AND HYDROXYL-CONTAINING DRUGS Baikang (Suzhou) Co., Ltd (CN) 2016-10-12 EP claimed
WO-2016040081-A1 QUINAZOLINE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS JANSSEN PHARMACEUTICA NV (BE) 2016-03-17 WO claimed
US-20150246958-A1 BIOREVERSABLE PROMOIETIES FOR NITROGEN-CONTAINING AND HYDROXYL-CONTAINING DRUGS BAIKANG (SUZHOU) CO., LTD (CN) 2015-09-03 US claimed
WO-2015081891-A1 BIOREVERSABLE PROMOIETIES FOR NITROGEN-CONTAINING AND HYDROXYL-CONTAINING DRUGS BAIKANG (SUZHOU) CO., LTD (CN) 2015-06-11 WO claimed
US-20130035364-A1 BENZYLIDENE-INDOLINONE COMPOUNDS AND THEIR MEDICAL USE NATIONAL UNIVERSITY OF SINGAPORE (SG) 2013-02-07 US claimed
EP-0477049-B1 Amido-3-pyrazole derivatives, process for their preparation and pharmaceutical compositions containing them SANOFI SYNTHELABO (FR) 1999-12-01 EP claimed
EP-4396259-B1 COMPOSITION MERCK PATENT GMBH (DE) 2026-02-04 EP disclosed
US-20240352181-A1 COMPOSITION MERCK PATENT GMBH (DE) 2024-10-24 US disclosed
EP-4429653-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER Reverspah LLC (US) 2024-09-18 EP disclosed
US-20230226105-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER REVERSPAH LLC (US) 2023-07-20 US disclosed
WO-2008116909-A1 PURINYL DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS NEUROSEARCH A/S (DK) 2008-10-02 WO disclosed
WO-2008116910-A1 PURINYL DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS NEUROSEARCH A/S (DK) 2008-10-02 WO disclosed
US-6906007-B2 Phenyl-substituted 5,6-dihydropyrone derivatives for use as pesticides and herbicides BAYER CROPSCIENCE AG (DE) 2005-06-14 US disclosed
US-20040102516-A1 Phenyl-substituted 5,6-dihydrophyne derivatives for use as pesticides and herbicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2004-05-27 US disclosed
EP-0186027-A2 Mixture of different dihydropyridines, process for its manufacture and its use in medicines BAYER AG (DE) 1986-07-02 EP disclosed