SCHEMBL1828804

SCHEMBL1828804

CNc1ccc2c(c1)Sc1cc(NC)ccc1N2C(=O)N(C)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ SNCA P37840 3/20 0.44
▸ BCHE P06276 9/20 0.43
▸ MEN1 O00255 1/20 0.42
▸ MAPK1 P28482 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ POLB P06746 1/20 0.38
▸ ATM Q13315 1/20 0.38
▸ ACHE P22303 2/20 0.37
▸ NOX1 Q9Y5S8 3/20 0.36
▸ CYP2D6 P10635 1/20 0.35
▸ TSHR P16473 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30851251 0.82 NOX1 (0.54) SNCABCHEMEN1MAPK1KMT2A
SCHEMBL1926804 0.82 NOX1 (0.54) SNCABCHEMEN1MAPK1KMT2A
SCHEMBL244957 0.80 MAPK1 (0.64) SNCABCHEMEN1MAPK1KMT2A
SCHEMBL18408661 0.78 MAPK1 (0.55) SNCABCHEMEN1MAPK1KMT2A
SCHEMBL396463 0.78 BCHE (0.61) SNCABCHEKMT2AACHENOX1
SCHEMBL12955933 0.76 MEN1 (0.63) SNCABCHEMEN1MAPK1KMT2A
SCHEMBL8223437 0.75 NOX1 (0.46) SNCABCHEMEN1MAPK1KMT2A
SCHEMBL22726491 0.75 MAPK1 (0.54) SNCABCHEMEN1MAPK1KMT2A
SCHEMBL15963115 0.74 MEN1 (0.81) SNCABCHEMEN1MAPK1KMT2A
SCHEMBL14142982 0.72 BCHE (0.61) SNCABCHEACHENOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12264356-B2 Method for determining sensitivity to SGLT2 inhibitor and sensitivity marker for SGLT2 inhibitor NIHON UNIVERSITY (JP) 2025-04-01 — — US disclosed
US-20200347458-A1 METHOD FOR DETERMINING SENSITIVITY TO SGLT2 INHIBITOR AND SENSITIVITY MARKER FOR SGLT2 INHIBITOR NIHON UNIVERSITY (JP) 2020-11-05 — — US disclosed
CN-111575339-A 1, 5-anhydroglucitol enzymatic quantitative method and reagent therefor 王学忠 2020-08-25 — — CN disclosed
EP-2319937-B1 BLOOD COMPONENT MEASUREMENT METHOD UTILIZING HEMOLYZED WHOLE BLOOD, AND KIT FOR THE METHOD NIPPON KAYAKU KK (JP) 2016-01-27 — — EP disclosed
US-8883439-B2 Blood component measurement method utilizing hemolyzed whole blood, and kit for the method NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2014-11-11 — — US disclosed
US-8753832-B2 Method of assaying 1,5 anhydroglucitol by using whole blood and measurement kit NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2014-06-17 — — US disclosed
US-20110165608-A1 BLOOD COMPONENT MEASUREMENT METHOD UTILIZING HEMOLYZED WHOLE BLOOD, AND KIT FOR THE METHOD NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-07 — — US disclosed
EP-1895303-B1 METHOD OF ASSAYING 1, 5-ANHYDROGLUCITOL BY USING WHOLE BLOOD NIPPON KAYAKU KK (JP) 2011-05-11 — — EP disclosed
EP-2319937-A1 BLOOD COMPONENT MEASUREMENT METHOD UTILIZING HEMOLYZED WHOLE BLOOD, AND KIT FOR THE METHOD Nippon Kayaku Kabushiki Kaisha (JP) 2011-05-11 — — EP disclosed
US-20100075352-A1 Method of assaying bolld component by using whole blood and measurement kit NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-03-25 — — US disclosed
EP-1895303-A1 METHOD OF ASSAYING BLOOD COMPONENT BY USING WHOLE BLOOD AND MEASUREMENT KIT Nippon Kayaku Kabushiki Kaisha (JP) 2008-03-05 — — EP disclosed
US-6448029-B1 USING NUCLEOTIDE DIPHOSPHATE OR TRIPHOSPHATE KYOWA MEDEX CO., LTD. (JP) 2002-09-10 — — US disclosed
EP-1213357-A2 Method and reagent for quantitative determination of 1, 5-Anhydroglucitol KYOWA MEDEX CO., LTD. (JP) 2002-06-12 — — EP disclosed
US-20020068310-A1 Method and reagant for quantitative determination of 1,5-anhydroglucitol KYOWA MEDEX CO., LTD. (JP) 2002-06-06 — — US disclosed
US-6309852-B1 CONTACTING THE SAMPLE WITH AN ENZYME SUCH AS NUCLEOSIDE DIPHOSPHATE, TRIPHOSPHATE AND NUCLEOSIDE DEPENDENT ENZYMES SYSTEM WHICH CONVERTS GLUCOSE INTO FRUCTOSE 1,6-DIPHOSPHATE AND 1,5-ANHYDROGLUCITOL (1,5-AG)TO 1,5-AG-6-PHOSPHATE KYOWA MEDEX CO., LTD. (JP) 2001-10-30 — — US disclosed
CN-1257128-A Method for quantifying 1,5-anhydrosorbierite and quantitative reagent KYOWA MEDEX CO LTD (JP) 2000-06-21 — — CN disclosed
EP-1008657-A2 Method and reagent for quantitative determination of 1,5-anhydroglucitol KYOWA MEDEX CO., LTD. (JP) 2000-06-14 — — EP disclosed
EP-0843019-A2 Method for determination of specific nucleic acid sequence, and a reagent therefor KYOWA MEDEX CO., LTD. (JP) 1998-05-20 — — EP disclosed
US-5426033-A Accurate quantitative analysis KYOWA MEDEX CO., LTD. (JP) 1995-06-20 — — US disclosed
EP-0608795-A1 Method for enzymatic determination of substrate after enzymatically removing galactose Kyowa Medex Co. Ltd. (JP) 1994-08-03 — — EP disclosed
Send feedback