SCHEMBL18288745

SCHEMBL18288745

C=Cc1ccc(/C=C/C(=O)Oc2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.66
HTR1A P08908 1/20 0.54
MAOB P27338 2/20 0.49
RAD51 Q06609 1/20 0.49
MEN1 O00255 3/20 0.48
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
LMNA P02545 3/20 0.46
ALDH1A1 P00352 2/20 0.46
SRD5A2 P31213 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CA12 O43570 1/20 0.46
AKR1B10 O60218 1/20 0.46
AKR1B1 P15121 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14394756 1.00 KMT2A (0.66) KMT2AHTR1AMAOBRAD51MEN1
SCHEMBL8756097 0.95 KMT2A (0.73) KMT2AHTR1AMAOBMEN1ESR1
SCHEMBL8756092 0.95 KMT2A (0.73) KMT2AHTR1AMAOBMEN1ESR1
Phenyl Cinnamate SCHEMBL1055161 0.87 KMT2A (0.77) KMT2AHTR1AMAOBMEN1ESR1
Phenyl Cinnamate SCHEMBL1055160 0.87 KMT2A (0.77) KMT2AHTR1AMAOBMEN1ESR1
SCHEMBL15908399 0.84 KMT2A (0.68) KMT2AHTR1AMAOBRAD51MEN1
SCHEMBL14634510 0.84 KMT2A (0.68) KMT2AHTR1AMAOBMEN1ESR1
SCHEMBL17802341 0.84 KMT2A (0.68) KMT2AHTR1AMAOBRAD51MEN1
SCHEMBL14634511 0.84 KMT2A (0.68) KMT2AHTR1AMAOBMEN1ESR1
SCHEMBL14634502 0.84 KMT2A (0.73) KMT2AHTR1AMAOBRAD51MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10017697-B2 Thermosetting composition with photo-alignment property, alignment layer, substrate with alignment layer, retardation plate, and device DAI NIPPON PRINTING CO., LTD. (JP) 2018-07-10 US disclosed
US-10017696-B2 Thermosetting composition with photo-alignment property, alignment layer, substrate with alignment layer, retardation plate, and device DAI NIPPON PRINTING CO., LTD. (JP) 2018-07-10 US disclosed
US-10017697-B2 Thermosetting composition with photo-alignment property, alignment layer, substrate with alignment layer, retardation plate, and device DAI NIPPON PRINTING CO., LTD. (JP) 2018-07-10 US disclosed
US-10017696-B2 Thermosetting composition with photo-alignment property, alignment layer, substrate with alignment layer, retardation plate, and device DAI NIPPON PRINTING CO., LTD. (JP) 2018-07-10 US disclosed
US-20160355735-A1 THERMOSETTING COMPOSITION WITH PHOTO-ALIGNMENT PROPERTY, ALIGNMENT LAYER, SUBSTRATE WITH ALIGNMENT LAYER, RETARDATION PLATE, AND DEVICE DAI NIPPON PRINTING CO., LTD. (JP) 2016-12-08 US disclosed
US-20160355735-A1 THERMOSETTING COMPOSITION WITH PHOTO-ALIGNMENT PROPERTY, ALIGNMENT LAYER, SUBSTRATE WITH ALIGNMENT LAYER, RETARDATION PLATE, AND DEVICE DAI NIPPON PRINTING CO., LTD. (JP) 2016-12-08 US disclosed
US-20160355736-A1 THERMOSETTING COMPOSITION WITH PHOTO-ALIGNMENT PROPERTY, ALIGNMENT LAYER, SUBSTRATE WITH ALIGNMENT LAYER, RETARDATION PLATE, AND DEVICE DAI NIPPON PRINTING CO., LTD. (JP) 2016-12-08 US disclosed
US-20160355736-A1 THERMOSETTING COMPOSITION WITH PHOTO-ALIGNMENT PROPERTY, ALIGNMENT LAYER, SUBSTRATE WITH ALIGNMENT LAYER, RETARDATION PLATE, AND DEVICE DAI NIPPON PRINTING CO., LTD. (JP) 2016-12-08 US disclosed