SCHEMBL18291384 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	HTR2C	P28335	11/20	0.44

▸	PIM1	P11309	2/20	0.42

▸	PIM3	Q86V86	2/20	0.42

▸	PIM2	Q9P1W9	2/20	0.42

▸	HTR2A	P28223	4/20	0.41

▸	HTR2B	P41595	2/20	0.41

▸	KCNH2	Q12809	2/20	0.41

▸	RAD52	P43351	1/20	0.41

▸	ROCK2	O75116	1/20	0.39

▸	ROCK1	Q13464	1/20	0.39

▸	GSK3B	P49841	2/20	0.38

▸	TLR9	Q9NR96	2/20	0.38

▸	TLR8	Q9NR97	2/20	0.38

▸	TLR7	Q9NYK1	2/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL22489453	0.83	BPTF (0.55)	HTR2CHTR2AHTR2B
SCHEMBL20037535	0.83	HTR2C (0.41)	HTR2CPIM1PIM3PIM2HTR2A
SCHEMBL30609645	0.83	BPTF (0.55)	HTR2CHTR2AHTR2B
SCHEMBL17884816	0.83	BPTF (0.55)	HTR2CHTR2AHTR2B
SCHEMBL20038062	0.83	HTR2C (0.41)	HTR2CPIM1PIM3PIM2HTR2A
SCHEMBL18291427	0.83	HTR2C (0.41)	HTR2CPIM1PIM3PIM2HTR2A
SCHEMBL20249160	0.81	HTR2C (0.39)	HTR2CPIM1PIM3PIM2HTR2A
SCHEMBL20249167	0.81	HTR2C (0.39)	HTR2CPIM1PIM3PIM2HTR2A
SCHEMBL18291325	0.80	IRAK4 (0.37)	HTR2CHTR2AHTR2BKCNH2
SCHEMBL13491002	0.79	PIM1 (0.45)	HTR2CPIM1PIM3PIM2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2016194831-A1	PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF	帝人ファーマ株式会社	2016-12-08	—	—	WO	disclosed