Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | AOC1 | P19801 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28188152 | 0.84 | TP53 (0.39) | TP53SMN1; SMN2GAARBP4NPC1 | |
| SCHEMBL692343 | 0.79 | — | — | |
| SCHEMBL5163162 | 0.78 | TP53 (0.40) | TP53SMN1; SMN2GAARBP4NPC1 | |
| Bromide SCHEMBL28919507 | 0.77 | TP53 (0.51) | TP53SMN1; SMN2GAANPC1RAB9A | |
| Water SCHEMBL5369991 | 0.77 | TP53 (0.51) | TP53SMN1; SMN2GAANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL27472182 | 0.77 | TP53 (0.51) | TP53SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL28300836 | 0.75 | — | — | |
| SCHEMBL8908834 | 0.75 | TP53 (0.43) | TP53SMN1; SMN2GAARBP4NPC1 | |
| SCHEMBL9016443 | 0.74 | TP53 (0.42) | TP53SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL1720771 | 0.74 | KDM4E (0.46) | TP53SMN1; SMN2GAARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115043844-B | TRK kinase inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-110582493-B | Benzoxazole derivatives as immunomodulators | 因赛特公司 | 2024-03-08 | — | — | CN | disclosed |
| WO-2024046420-A1 | FUSED BICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2024-03-07 | — | — | WO | disclosed |
| WO-2024032598-A1 | TGF-β INHIBITOR COMPOUND AND USE THEREOF | 河南迈英诺医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |
| WO-2024032589-A1 | TGF-β INHIBITOR COMPOUND AND USE THEREOF | 河南迈英诺医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |
| CN-117534686-A | TGF-beta inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-117534675-A | TGF-beta inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-113227068-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-06-13 | — | — | CN | disclosed |
| EP-4096668-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |
| CN-113227068-A | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-107849047-B | Biphenyl derivative, preparation method and medical application thereof | 四川海思科制药有限公司 | 2021-01-15 | — | — | CN | disclosed |
| WO-2020054788-A1 | IMIDAZOPYRIDINONE COMPOUND | キッセイ薬品工業株式会社 | 2020-03-19 | — | — | WO | disclosed |
| CN-107849047-A | Biphenyl derivative, preparation method and medical application thereof | 四川海思科制药有限公司 | 2018-03-27 | — | — | CN | disclosed |
| EP-2315768-A1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | UCB Pharma, S.A. (BE) | 2011-05-04 | — | — | EP | disclosed |
| WO-2009153554-A1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2009-12-23 | — | — | WO | disclosed |