Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | HPD | P32754 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1826000 | 0.90 | CNR1 (0.52) | HDAC6PIK3CDCNR1CNR2KMT2A | |
| SCHEMBL1827713 | 0.82 | CNR1 (0.52) | PIK3CDCNR1CNR2KMT2AALDH1A1 | |
| SCHEMBL1824391 | 0.80 | CNR1 (0.53) | HDAC6PIK3CDCNR1CNR2KMT2A | |
| SCHEMBL10973972 | 0.78 | CNR1 (0.57) | CNR1CNR2KMT2AALDH1A1KDM4E | |
| SCHEMBL10975710 | 0.77 | CNR1 (0.54) | CNR1CNR2PDE10AKMT2AALDH1A1 | |
| SCHEMBL11075597 | 0.77 | CNR1 (0.56) | CNR1CNR2PDE10AKMT2AALDH1A1 | |
| SCHEMBL11071494 | 0.76 | CNR1 (0.48) | PIK3CDCNR1CNR2ALDH1A1KDM4E | |
| SCHEMBL11081203 | 0.76 | CNR1 (0.51) | CNR1CNR2KMT2AALDH1A1LMNA | |
| SCHEMBL11073415 | 0.75 | CNR1 (0.48) | PIK3CDCNR1CNR2ALDH1A1KDM4E | |
| SCHEMBL11040498 | 0.74 | CNR1 (0.51) | CNR1CNR2KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2319839-A1 | Quinazolinone derivatives and their use as CB agonists | Novartis AG (CH) | 2011-05-11 | — | — | EP | disclosed |