SCHEMBL18296752

SCHEMBL18296752

N=C(N)NCCCCCNC(=N)NCCCOc1ccc(C(=N)N)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 3/20 0.64
F2 P00734 2/20 0.64
ST14 Q9Y5Y6 2/20 0.64
TMPRSS2 O15393 2/20 0.64
PLAU P00749 1/20 0.64
PRMT5 O14744 1/20 0.64
SLC22A2 O15244 1/20 0.64
SLC22A1 O15245 1/20 0.64
PTP4A3 O75365 1/20 0.64
SLC22A3 O75751 1/20 0.64
F10 P00742 1/20 0.64
PLG P00747 1/20 0.64
S100B P04271 1/20 0.64
CHRM2 P08172 1/20 0.64
CHRM4 P08173 1/20 0.64
CHRM5 P08912 1/20 0.64
ADRA2A P08913 1/20 0.64
CYP2D6 P10635 1/20 0.64
AOC1 P19801 1/20 0.64
MAOA P21397 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18296457 1.00 PRMT1 (0.64) PRMT1F2ST14TMPRSS2PLAU
SCHEMBL18296682 1.00 PRMT1 (0.64) PRMT1F2ST14TMPRSS2PLAU
SCHEMBL18296756 1.00 PRMT1 (0.64) PRMT1F2ST14TMPRSS2PLAU
SCHEMBL18296571 0.99 PRMT1 (0.62) PRMT1F2ST14TMPRSS2PLAU
SCHEMBL18296508 0.99 PRMT1 (0.62) PRMT1F2ST14TMPRSS2PLAU
SCHEMBL18296573 0.99 PRMT1 (0.62) PRMT1F2ST14TMPRSS2PLAU
SCHEMBL18296433 0.97 PRMT1 (0.69) PRMT1F2ST14TMPRSS2PLAU
SCHEMBL18296757 0.97 PRMT1 (0.69) PRMT1F2ST14TMPRSS2PLAU
SCHEMBL18296450 0.97 PRMT1 (0.69) PRMT1F2ST14TMPRSS2PLAU
SCHEMBL18296411 0.97 PRMT1 (0.69) PRMT1F2ST14TMPRSS2PLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180146677-A1 GUANICIDE COMPOUND AND FUNGICIDE NIPPON SODA CO., LTD. (JP) 2018-05-31 US disclosed
WO-2016195077-A1 GUANIDINE COMPOUND AND BACTERICIDE 日本曹達株式会社 2016-12-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180146677-A1 GUANICIDE COMPOUND AND FUNGICIDE GUCY1A2, GUCY1B2, GUCY1A1 PRMT1 18/4885F2 4057/4885ST14 3279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.