Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27657800 | 0.82 | NPC1 (0.41) | NPC1TSHRCYP1A2CHRM2CHRM4 | |
| SCHEMBL2478567 | 0.82 | NPC1 (0.41) | NPC1TSHRCYP1A2CHRM2CHRM4 | |
| SCHEMBL4677677 | 0.80 | NPC1 (0.39) | NPC1TSHRCYP1A2CHRM2CHRM4 | |
| SCHEMBL4677672 | 0.80 | NPC1 (0.39) | NPC1TSHRCYP1A2CHRM2CHRM4 | |
| SCHEMBL16815032 | 0.80 | NPC1 (0.39) | NPC1TSHRCYP1A2CHRM2CHRM4 | |
| SCHEMBL4672967 | 0.78 | NPC1 (0.38) | NPC1TSHRCYP1A2CHRM2CHRM4 | |
| SCHEMBL3413585 | 0.78 | NPC1 (0.42) | NPC1TSHRCYP1A2CHRM2CHRM4 | |
| SCHEMBL4676587 | 0.78 | NPC1 (0.38) | NPC1TSHRCYP1A2CHRM2CHRM4 | |
| SCHEMBL4672971 | 0.78 | NPC1 (0.38) | NPC1TSHRCYP1A2CHRM2CHRM4 | |
| SCHEMBL4676580 | 0.78 | NPC1 (0.38) | NPC1TSHRCYP1A2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3307672-A1 | HYBRID NANOPARTICLES CONTAINING DENDRONS, METHODS OF PRODUCING SUCH HYBRID NANOPARTICLES, AND USES THEREOF | Rhodia Operations (FR) | 2018-04-18 | — | — | EP | disclosed |
| WO-2016201310-A1 | HYBRID NANOPARTICLES CONTAINING DENDRONS, METHODS OF PRODUCING SUCH HYBRID NANOPARTICLES, AND USES THEREOF | RHODIA OPERATIONS (FR) | 2016-12-15 | — | — | WO | disclosed |