Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 19/20 | 0.84 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.58 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18301864 | 0.93 | P2RX4 (0.80) | P2RX4KCNJ5KCNJ3 | |
| SCHEMBL30591487 | 0.92 | P2RX4 (1.00) | P2RX4 | |
| SCHEMBL18301647 | 0.92 | P2RX4 (1.00) | P2RX4 | |
| SCHEMBL18301824 | 0.90 | P2RX4 (0.86) | P2RX4 | |
| SCHEMBL31290043 | 0.90 | P2RX4 (0.86) | P2RX4 | |
| SCHEMBL30591595 | 0.84 | P2RX4 (1.00) | P2RX4 | |
| SCHEMBL18301658 | 0.84 | P2RX4 (1.00) | P2RX4 | |
| SCHEMBL18301830 | 0.84 | P2RX4 (0.78) | P2RX4 | |
| SCHEMBL18301820 | 0.84 | P2RX4 (0.79) | P2RX4 | |
| SCHEMBL18301617 | 0.83 | P2RX4 (0.83) | P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3307715-A1 | AROMATIC SULFONAMIDE DERIVATIVES | Bayer Pharma Aktiengesellschaft (DE) | 2018-04-18 | — | — | EP | claimed |
| WO-2016198374-A1 | AROMATIC SULFONAMIDE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-15 | — | — | WO | claimed |