Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.45 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5295046 | 0.88 | DHODH (0.65) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL3894378 | 0.87 | DHODH (0.63) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL15053652 | 0.85 | DHODH (0.60) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL2968074 | 0.85 | DHODH (0.60) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL18988013 | 0.84 | DHODH (0.63) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL10862397 | 0.83 | DHODH (0.62) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL18987970 | 0.82 | DHODH (0.60) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL18988001 | 0.82 | DHODH (0.60) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL13664760 | 0.81 | DHODH (0.62) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL10863692 | 0.80 | DHODH (0.90) | DHODHNPSR1MAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016199943-A1 | HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-12-15 | — | — | WO | disclosed |