Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19235659 | 1.00 | TSHR (0.40) | TSHRKDM4EL3MBTL1NISCHHTT | |
| SCHEMBL18306407 | 1.00 | TSHR (0.40) | TSHRKDM4EL3MBTL1NISCHHTT | |
| SCHEMBL17598373 | 1.00 | TSHR (0.40) | TSHRKDM4EL3MBTL1NISCHHTT | |
| SCHEMBL17551809 | 1.00 | TSHR (0.40) | TSHRKDM4EL3MBTL1NISCHHTT | |
| SCHEMBL18306404 | 1.00 | TSHR (0.40) | TSHRKDM4EL3MBTL1NISCHHTT | |
| SCHEMBL17551808 | 0.92 | TSHR (0.35) | TSHRKDM4EALOX15LMNAALDH1A1 | |
| SCHEMBL17551744 | 0.92 | TSHR (0.35) | TSHRKDM4EALOX15LMNAALDH1A1 | |
| SCHEMBL17537095 | 0.90 | TSHR (0.37) | TSHRKDM4EL3MBTL1NISCHHTT | |
| SCHEMBL17537170 | 0.90 | TSHR (0.37) | TSHRKDM4EL3MBTL1NISCHHTT | |
| SCHEMBL17537119 | 0.90 | TSHR (0.37) | TSHRKDM4EL3MBTL1NISCHHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9517988-B2 | Phenol derivative and preparation method and use in medicine thereof | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2016-12-13 | — | — | US | disclosed |