Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13877872 | 0.81 | CYP3A4 (0.35) | CYP3A4 | |
| SCHEMBL13884626 | 0.81 | CYP3A4 (0.35) | CYP3A4 | |
| SCHEMBL13877839 | 0.75 | CYP3A4 (0.32) | CYP3A4 | |
| SCHEMBL18083771 | 0.75 | CYP3A4 (0.32) | CYP3A4 | |
| SCHEMBL18306932 | 0.75 | CYP3A4 (0.32) | CYP3A4 | |
| SCHEMBL18306961 | 0.74 | CYP3A4 (0.32) | CYP3A4 | |
| SCHEMBL19264322 | 0.72 | CYP3A4 (0.32) | CYP3A4 | |
| SCHEMBL19264728 | 0.72 | CYP3A4 (0.36) | CYP3A4 | |
| SCHEMBL274597 | 0.71 | CYP3A4 (0.30) | CYP3A4 | |
| SCHEMBL15139329 | 0.70 | CYP3A4 (0.31) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3208269-A1 | INHIBITORS OF C-FMS KINASE | Janssen Pharmaceutica N.V. (BE) | 2017-08-23 | — | — | EP | disclosed |
| EP-2215079-B1 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2016-12-14 | — | — | EP | disclosed |