Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15743901 | 0.83 | CHRNA7 (0.66) | CHRNA7KCNH2 | |
| SCHEMBL21262667 | 0.82 | CHRNA7 (0.64) | CHRNA7KCNH2 | |
| SCHEMBL13657926 | 0.79 | CHRNA7 (0.61) | CHRNA7KCNH2 | |
| SCHEMBL13662093 | 0.79 | CHRNA7 (0.61) | CHRNA7KCNH2 | |
| SCHEMBL20492047 | 0.77 | MAP3K12 (0.47) | CHRNA7KCNH2 | |
| SCHEMBL20491966 | 0.77 | MAP3K12 (0.47) | CHRNA7KCNH2 | |
| SCHEMBL24681527 | 0.76 | CDK4 (0.47) | CHRNA7KCNH2 | |
| SCHEMBL15832593 | 0.75 | CHRNA7 (0.56) | CHRNA7KCNH2 | |
| SCHEMBL2944370 | 0.75 | CHRNA7 (0.67) | CHRNA7KCNH2 | |
| SCHEMBL15832590 | 0.75 | CHRNA7 (0.56) | CHRNA7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265607-B1 | PYRIMIDINE-2-AMINE COMPOUNDS AND THEIR USE AS INHIBITORS OF JAK KINASES | RIGEL PHARMACEUTICALS INC (US) | 2016-12-14 | — | — | EP | disclosed |