Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.32 |
| ▸ | POLRMT | O00411 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10120830 | 0.98 | TMPRSS2 (0.46) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL24119259 | 0.91 | TMPRSS2 (0.39) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL22096270 | 0.91 | TMPRSS2 (0.44) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL18308498 | 0.90 | TMPRSS2 (0.40) | TMPRSS2 | |
| SCHEMBL20762105 | 0.90 | TMPRSS2 (0.44) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL20878440 | 0.88 | TMPRSS2 (0.42) | TMPRSS2RIPK1 | |
| SCHEMBL10120820 | 0.88 | TMPRSS2 (0.42) | TMPRSS2RIPK1 | |
| SCHEMBL18310258 | 0.88 | TMPRSS2 (0.42) | TMPRSS2RIPK1 | |
| SCHEMBL10120053 | 0.88 | TMPRSS2 (0.40) | TMPRSS2 | |
| SCHEMBL24975093 | 0.87 | TMPRSS2 (0.44) | TMPRSS2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9949994-B2 | Methods for treating Filoviridae virus infections | GILEAD SCIENCES, INC. (US) | 2018-04-24 | — | — | US | disclosed |
| US-20160361330-A1 | METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES, INC. | 2016-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160361330-A1 | METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS | PNP, PRPF4, RPIA | TMPRSS2 1951/4885RIPK1 2292/4885POLRMT 104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.