⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10434492 | 0.97 | EP300 (0.52) | — | |
| SCHEMBL16934140 | 0.97 | EP300 (0.52) | — | |
| SCHEMBL7647768 | 0.97 | EP300 (0.52) | — | |
| SCHEMBL30185872 | 0.97 | EP300 (0.52) | — | |
| SCHEMBL16933784 | 0.97 | EP300 (0.52) | — | |
| SCHEMBL11290158 | 0.92 | — | — | |
| SCHEMBL28387728 | 0.81 | — | — | |
| SCHEMBL16969891 | 0.81 | — | — | |
| SCHEMBL16969887 | 0.81 | — | — | |
| SCHEMBL12074800 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324404-B2 | 3-thia-10-aza-phenanthrene derivatives | NYCOMED GMBH (DE) | 2012-12-04 | — | — | US | disclosed |
| EP-1797098-B1 | 3-OXA-10-AZA-PHENANTHRENES AS PDE4 OR PDE3/4 INHIBITORS | NYCOMED GMBH (DE) | 2011-05-04 | — | — | EP | disclosed |
| US-7838521-B2 | 3-oxa-10-aza-phenanthrenes | NYCOMED GMBH (DE) | 2010-11-23 | — | — | US | disclosed |
| US-20090239895-A1 | Novel 3-thia-10-aza-phenanthrene derivatives | NYCOMED GMBH (DE) | 2009-09-24 | — | — | US | disclosed |
| US-7589205-B2 | phosphodiesterase inhibitor; antiinflammatory agent; 3-thia-10-aza-phenanthrenes and iintermediates 3-(3,4-dialkoxy-phenyl)-tetrahydro-thiopyran-4-one and 3-(3,4-dialkoxy-phenyl)-1,1-dioxo-hexahydro-1-thiopyran-4-ylamine, useful for its preparation | NYCOMED GMBH (DE) | 2009-09-15 | — | — | US | disclosed |
| US-20080103168-A1 | Novel 3-Thia-10-Aza-Phenanthrene Derivatives | ATLANA PHARMA AG (DE) | 2008-05-01 | — | — | US | disclosed |
| US-20070259868-A1 | Novel 3-Oxa-10-Aza-Phenanthrenes | ALTANA PHARMA AG (DE) | 2007-11-08 | — | — | US | disclosed |
| EP-1797098-A2 | 3-OXA-10-AZA-PHENANTHRENES AS PDE4 OR PDE3/4 INHIBITORS | Altana Pharma AG (DE) | 2007-06-20 | — | — | EP | disclosed |
| EP-1791847-A2 | NOVEL 3-THIA-10-AZA-PHENANTHRENE DERIVATIVES | Altana Pharma AG (DE) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006027345-A2 | NOVEL 3-THIA-10-AZA-PHENANTHRENE DERIVATIVES | ALTANA PHARMA AG (DE) | 2006-03-16 | — | — | WO | disclosed |
| WO-2006027344-A2 | 3-OXA-10-AZA-PHENANTHRENES AS PDE4 OR PDE3/4 INHIBITORS | ALTANA PHARMA AG (DE) | 2006-03-16 | — | — | WO | disclosed |