Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1051854 | 0.90 | RECQL (0.54) | RECQLEPHX1HSD11B1MGLLALDH1A1 | |
| Hydrochloric Acid SCHEMBL4597244 | 0.87 | RECQL (0.52) | RECQLEPHX1HSD11B1MGLLALDH1A1 | |
| SCHEMBL24134261 | 0.83 | — | — | |
| SCHEMBL29412339 | 0.77 | MAPT (0.32) | MAPTGAATSHR | |
| SCHEMBL6175234 | 0.74 | PHGDH (0.44) | PHGDHRECQLDPP4MAPTHSD11B1 | |
| SCHEMBL418958 | 0.74 | SMN1; SMN2 (0.50) | PHGDHRECQLDPP4MAPTHSD11B1 | |
| SCHEMBL6175241 | 0.74 | PHGDH (0.44) | PHGDHRECQLDPP4MAPTHSD11B1 | |
| SCHEMBL13827669 | 0.74 | SMN1; SMN2 (0.50) | PHGDHRECQLDPP4MAPTHSD11B1 | |
| SCHEMBL4498432 | 0.74 | PHGDH (0.44) | PHGDHRECQLDPP4MAPTHSD11B1 | |
| SCHEMBL13827670 | 0.74 | SMN1; SMN2 (0.50) | PHGDHRECQLDPP4MAPTHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573920-A | Indoles for use in influenza virus infection | 爱尔兰詹森科学公司 | 2017-04-19 | — | — | CN | disclosed |
| WO-2016199761-A1 | DIFLUOROMETHYLENE COMPOUNDS | 石原産業株式会社 | 2016-12-15 | — | — | WO | disclosed |