Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.65 |
| ▸ | TNK1 | Q13470 | 9/20 | 0.64 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18313999 | 0.94 | PARP1 (0.74) | PARP1TNK1TNK2 | |
| SCHEMBL18314003 | 0.94 | PARP1 (0.73) | PARP1TNK1TNK2 | |
| SCHEMBL18314072 | 0.92 | PARP1 (0.74) | PARP1TNK1TNK2 | |
| SCHEMBL20249552 | 0.90 | PARP1 (0.69) | PARP1TNK1TNK2 | |
| SCHEMBL18314156 | 0.88 | PARP1 (0.74) | PARP1TNK1TNK2 | |
| SCHEMBL18314071 | 0.87 | PARP1 (0.74) | PARP1TNK1TNK2 | |
| SCHEMBL18313997 | 0.86 | PARP1 (0.81) | PARP1TNK1TNK2 | |
| SCHEMBL18313998 | 0.85 | PARP1 (0.73) | PARP1TNK1TNK2 | |
| SCHEMBL18313996 | 0.85 | PARP1 (0.75) | PARP1TNK1TNK2 | |
| SCHEMBL20249580 | 0.84 | PARP1 (0.80) | PARP1TNK1TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312177-B1 | TRICYCLIC DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | ONCONIC THERAPEUTICS INC (KR) | 2021-04-14 | — | — | EP | claimed |
| US-10464919-B2 | Tricyclic derivative compound, method for preparing same, and pharmaceutical composition comprising same | JE IL PHARMACEUTICAL CO., LTD. (KR) | 2019-11-05 | — | — | US | claimed |
| US-20180162834-A1 | Tricyclic Derivative Compound, Method for Preparing Same, and Pharmaceutical Composition Comprising Same | ONCONIC THERAPEUTICS INC. (KR) | 2018-06-14 | — | — | US | claimed |
| EP-3312177-B1 | TRICYCLIC DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | ONCONIC THERAPEUTICS INC (KR) | 2021-04-14 | — | — | EP | disclosed |
| US-10464919-B2 | Tricyclic derivative compound, method for preparing same, and pharmaceutical composition comprising same | JE IL PHARMACEUTICAL CO., LTD. (KR) | 2019-11-05 | — | — | US | disclosed |
| US-10464919-B2 | Tricyclic derivative compound, method for preparing same, and pharmaceutical composition comprising same | JE IL PHARMACEUTICAL CO., LTD. (KR) | 2019-11-05 | — | — | US | disclosed |
| US-20180162834-A1 | Tricyclic Derivative Compound, Method for Preparing Same, and Pharmaceutical Composition Comprising Same | ONCONIC THERAPEUTICS INC. (KR) | 2018-06-14 | — | — | US | disclosed |
| US-20180162834-A1 | Tricyclic Derivative Compound, Method for Preparing Same, and Pharmaceutical Composition Comprising Same | ONCONIC THERAPEUTICS INC. (KR) | 2018-06-14 | — | — | US | disclosed |
| WO-2016200101-A2 | TRICYCLIC DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 제일약품주식회사 | 2016-12-15 | — | — | WO | disclosed |
| US-9261781-B2 | Preparation of norbornane-based PAC ballasts | SUMITOMO BAKELITE CO., LTD. (JP) | 2016-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180162834-A1 | Tricyclic Derivative Compound, Method for Preparing Same, and Pharmaceutical Composition Comprising Same | TNKS, TNKS2, PARP1 | PARP1 3/4885TNK1 26/4885TNK2 53/4885 |
| US-10464919-B2 | Tricyclic derivative compound, method for preparing same, and pharmaceutical composition comprising same | TNKS, TNKS2, PARP1 | PARP1 3/4885TNK1 26/4885TNK2 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.