Pentachlorobenzene

Pentachlorobenzene

SCHEMBL183144

Clc1cc(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 1.00
HPGD P15428 6/20 0.59
HSD17B10 Q99714 6/20 0.59
TSHR P16473 6/20 0.59
MAPK1 P28482 3/20 0.59
HSP90AA1 P07900 2/20 0.59
CASP1 P29466 1/20 0.56
ALDH1A1 P00352 2/20 0.53
CRHBP P24387 1/20 0.47
CRHR2 Q13324 1/20 0.47
AHR P35869 9/20 0.46
AKR1B1 P15121 1/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
USP2 O75604 1/20 0.41
EGFR P00533 1/20 0.41
LMNA P02545 1/20 0.41
ESR1 P03372 1/20 0.41
ERBB2 P04626 1/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentachlorobenzene SCHEMBL11455164 1.00 CYP3A4 (1.00) CYP3A4HPGDHSD17B10TSHRMAPK1
Pentachlorobenzene SCHEMBL27460676 0.96 CYP3A4 (0.92) CYP3A4HPGDHSD17B10TSHRMAPK1
Pentachlorobenzene SCHEMBL29897265 0.96 CYP3A4 (0.92) CYP3A4HPGDHSD17B10TSHRMAPK1
Pentachlorobenzene SCHEMBL27732715 0.96 CYP3A4 (0.92) CYP3A4HPGDHSD17B10TSHRMAPK1
Pentachlorobenzene SCHEMBL28280575 0.96 CYP3A4 (0.92) CYP3A4HPGDHSD17B10TSHRMAPK1
Pentachlorobenzene SCHEMBL27484054 0.96 CYP3A4 (0.92) CYP3A4HPGDHSD17B10TSHRMAPK1
Pentachlorobenzene SCHEMBL1445743 0.96 CYP3A4 (0.92) CYP3A4HPGDHSD17B10TSHRMAPK1
Pentachlorobenzene SCHEMBL27699552 0.96 CYP3A4 (0.92) CYP3A4HPGDHSD17B10TSHRMAPK1
Pentachlorobenzene SCHEMBL27458674 0.96 CYP3A4 (0.92) CYP3A4HPGDHSD17B10TSHRMAPK1
Pentachlorobenzene SCHEMBL2139718 0.92 CYP3A4 (0.85) CYP3A4HPGDHSD17B10TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2392 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092926-A1 BIOLOGICAL STATUS CLASSIFICATION RANDOX LABORATORIES LTD (GB) 2026-04-02 US claimed
EP-4674280-A2 PALATABILITY ENHANCERS FOR PET FOOD, METHOD OF PREPARATION AND USES THEREOF Spécialités Pet Food (FR) 2026-01-07 EP claimed
US-20250346506-A1 Membrane-Mediated Electro-Oxidation-Reduction Deep Water Treatment Device and its Operation Method Thereof HARBIN INST TECHNOLOGY (CN) 2025-11-13 US claimed
CN-120160227-A Indoor air cleaning system 研能科技股份有限公司 2025-06-17 CN claimed
CN-120136732-A Method for purifying tetrachloro terephthalonitrile 江苏新河农用化工有限公司 2025-06-13 CN claimed
CN-119657120-A Hydrodechlorination catalyst and preparation method thereof 江苏扬农化工集团有限公司 2025-03-21 CN claimed
CN-119633844-A Selective hydrogenation dechlorination catalyst for chlorinated organic compounds and preparation method thereof 江苏扬农化工集团有限公司 2025-03-18 CN claimed
CN-119565645-A Continuous hydrogenation dechlorination catalyst and preparation method thereof 江苏扬农化工集团有限公司 2025-03-07 CN claimed
CN-119499686-A Device system and method for catalyzing and hydrogenating polychlorinated benzene 江苏瑞祥化工有限公司 2025-02-25 CN claimed
EP-4507742-A2 ELEMENTS FOR DE-TARGETING GENE EXPRESSION IN LIVER Encoded Therapeutics, Inc. (US) 2025-02-19 EP claimed
EP-0043303-A1 Process for the isomerization and/or rearrangement of polychlorobenzenes RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1982-01-06 EP claimed
US-4299668-A USING PENTACHLOROPHENOL MIXED WITH CERTAIN CHLORINATED AND/OR OXYGENATED COMPOUNDS INTERNATIONAL SYNTHETIC RUBBER CO., LTD. (GB) 1981-11-10 US claimed
EP-0035927-A1 Process for the preparation of chloroalkoxy benzenes RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1981-09-16 EP claimed
US-4238254-A CHLOROHYDROCARBON, METAL POWDER, RED PHOSPHORUS BUCK CHEMISCH-TECHNISCHE WERKE GMBH & CO. (DE) 1980-12-09 US claimed
US-4147732-A NITRATION OF PENTACHLOROBENZENE, SULFURIC ACID OLIN CORPORATION (US) 1979-04-03 US claimed
US-4138438-A NITRATION OF PENTACHLOROBENZENE, REACTING EXCESS NITRIC ACID WITH HYDROCHLORIC ACID, BY-PRODUCT INHIBITION OLIN CORPORATION (US) 1979-02-06 US claimed
US-4096005-A SILVER IODATE, HALOGENATED HYDROCARBONS NUCLEI ENGINEERING, INC. (US) 1978-06-20 US claimed
US-4057590-A FROM PENTACHLOROBENZENE AND NITRIC ACID OLIN CORPORATION (US) 1977-11-08 US claimed
US-4026955-A Preparation of pentachloronitrobenzene OLIN CORPORATION (US) 1977-05-31 US claimed
US-3983816-A COMPOSITIONS FOR PRODUCING FLICKERING SIGNALS THIOKOL CORPORATION (US) 1976-10-05 US claimed