Pyruvate

Pyruvate

SCHEMBL1831473

CC(=O)C(=O)O.CNC(C)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.40
KISS1R Q969F8 4/20 0.34
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
THPO P40225 1/20 0.33
FFAR3 O14843 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL1837737 0.88 TP53 (0.44) TP53KISS1RALDH1A1TSHRTHPO
Acetic Acid SCHEMBL1832154 0.88
Bicarbonate SCHEMBL1830890 0.84
Pyruvate SCHEMBL1837949 0.82 TP53 (0.40) TP53KISS1RALDH1A1TSHRTHPO
Lactic Acid SCHEMBL1836627 0.79 TP53 (0.69) TP53ALDH1A1TSHRCYP2D6CYP2C19
Pyruvate SCHEMBL21145134 0.77
SCHEMBL3075465 0.77
SCHEMBL16104649 0.77
SCHEMBL15452 0.77
Cadaverine Tartrate SCHEMBL1833969 0.77 TSHR (0.59) TP53ALDH1A1TSHRTHPOCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US claimed
CN-1997620-A Ionic liquids comprising nitrogen-containing cations UNIV YORK (GB) 2007-07-11 CN claimed
US-9328220-B2 Liquids INNOVIA FILMS LIMITED (GB) 2016-05-03 US disclosed
US-8992798-B2 Liquids INNOVIA FILMS LIMITED (GB) 2015-03-31 US disclosed
US-8784686-B2 Liquids INNOVIA FILMS LIMITED (GB) 2014-07-22 US disclosed
US-20140187684-A1 LIQUIDS INNOVIA FILMS LIMITED (GB) 2014-07-03 US disclosed
CN-1997620-B Ionic liquids comprising nitrogen-containing cations UNIV YORK 2012-10-03 CN disclosed
CN-102344379-A Ionic liquid containing nitrogen-containing cation UNIV YORK 2012-02-08 CN disclosed
US-20110257433-A1 LIQUIDS THE UNIVERSITY OF YORK (GB) 2011-10-20 US disclosed
EP-2322497-A1 Ionic liquids comprising nitrogen containing cations Innovia Films Limited (GB) 2011-05-18 EP disclosed
CN-101316810-A Ionic liquids BIONIQS LTD (GB) 2008-12-03 CN disclosed
US-20080221361-A1 Ionic Liquids BIONIQS LIMITED (GB) 2008-09-11 US disclosed
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US disclosed
CN-1997620-A Ionic liquids comprising nitrogen-containing cations UNIV YORK (GB) 2007-07-11 CN disclosed