Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 20/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18315729 | 0.92 | NAMPT (0.75) | NAMPTCYP2C9 | |
| SCHEMBL18315741 | 0.89 | NAMPT (0.78) | NAMPT | |
| SCHEMBL18315732 | 0.88 | NAMPT (0.80) | NAMPT | |
| SCHEMBL16858045 | 0.87 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL18315738 | 0.82 | NAMPT (0.76) | NAMPT | |
| SCHEMBL18315728 | 0.80 | NAMPT (0.77) | NAMPT | |
| SCHEMBL18315733 | 0.80 | NAMPT (0.77) | NAMPTCYP2C9 | |
| SCHEMBL18315739 | 0.79 | NAMPT (0.77) | NAMPT | |
| SCHEMBL16858035 | 0.78 | NAMPT (1.00) | NAMPT | |
| SCHEMBL18315736 | 0.78 | NAMPT (0.75) | NAMPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2820017-B1 | PYRIDINYL AND PYRIMIDINYL SULFOXIDE AND SULFONE DERIVATIVES | GENENTECH INC (US) | 2016-12-21 | — | — | EP | claimed |