Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 19/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.65 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18315906 | 0.92 | CALCRL (0.75) | CALCRLCYP3A4 | |
| SCHEMBL3766979 | 0.91 | CALCRL (0.77) | CALCRLCYP3A4RAMP1 | |
| SCHEMBL30231382 | 0.91 | CALCRL (0.77) | CALCRLCYP3A4RAMP1 | |
| SCHEMBL18315928 | 0.89 | CALCRL (0.70) | CALCRLCYP3A4RAMP1 | |
| SCHEMBL18315901 | 0.87 | CALCRL (0.84) | CALCRLCYP3A4 | |
| SCHEMBL18315922 | 0.87 | CALCRL (0.84) | CALCRLCYP3A4 | |
| SCHEMBL18315900 | 0.86 | CALCRL (0.72) | CALCRLCYP3A4 | |
| SCHEMBL13052536 | 0.85 | CALCRL (0.78) | CALCRLCYP3A4RAMP1 | |
| SCHEMBL13052535 | 0.85 | CALCRL (0.76) | CALCRLCYP3A4RAMP1 | |
| SCHEMBL13052520 | 0.84 | CALCRL (0.82) | CALCRLCYP3A4RAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539766-B1 | CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2016-12-21 | — | — | EP | claimed |