Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 18/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.84 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CALCA | P06881 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18315888 | 0.96 | CALCRL (0.78) | CALCRLCYP3A4CYP2D6 | |
| SCHEMBL18315892 | 0.95 | CALCRL (0.77) | CALCRLCYP3A4CYP2D6 | |
| SCHEMBL18315945 | 0.93 | CYP3A4 (0.85) | CALCRLCYP3A4CYP2D6 | |
| SCHEMBL18315904 | 0.93 | CALCRL (0.72) | CALCRLCYP3A4CYP2D6 | |
| SCHEMBL18315889 | 0.93 | CALCRL (0.84) | CALCRLCYP3A4CYP2D6 | |
| SCHEMBL18315903 | 0.92 | CALCRL (0.72) | CALCRLCYP3A4 | |
| SCHEMBL13053544 | 0.92 | CALCRL (1.00) | CALCRLCYP3A4CYP2D6CALCA | |
| SCHEMBL3607829 | 0.92 | CALCRL (1.00) | CALCRLCYP3A4CYP2D6CALCA | |
| SCHEMBL18315901 | 0.89 | CALCRL (0.84) | CALCRLCYP3A4 | |
| SCHEMBL18315922 | 0.89 | CALCRL (0.84) | CALCRLCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539766-B1 | CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2016-12-21 | — | — | EP | claimed |